The novel Mechanical Ventilator Milano for the COVID-19 pandemic

Abba, A.; Bianchi, G.; Martínez, M.; Margetak, P.; Ceccanti, A.; Retriere, F.; Papini, N.; Leyton, M.; Lee, L.; Basile, V.; Sher, A.; Gorini, G.; Romualdez, J.; Pope, A.; Accorsi, C.; Gabriele, F.; Gorel, P.; Giorgi, D.; Agnes, P.; Wada, M.; Galbiati, C.; McDonald, A.B.; Fernandes, C.; Dahl, C.E.; Lu, P.; Slutsky, A.; Russel, L.; Badia, C.; Hudson, K.; Daley, M.; Hawkins, W.; Salvo, P.; Hayashi, K.; Gillespie, S.; Napoli, P.; Martin, S.; Patel, A.; Reilly, T.; Nati, F.; James, C.C.; Pordes, S.; Martin, L.; Sala, S.; Giacomini, F.; Davignon, O.; Khan, S.; Grosso, G.; Parmeggiano, S.; Fiorillo, G.; Vanpagee, L.; Mohayai, T.; Fournier, R.D.; Wang, H.; Ferroni, F.; Breviario, M.; D'Avenio, G.; Brown, R.; Olchanski, K.; Schaubel, T.; Diaz Gomez Maqueo, P.; Salomoni, D.; Magni, G.; Kendziora, C.; Luzón, G.; Kochanek, I.; Riccobene, E.; Heavey, A.; Sablone, D.; Morrison, B.; Hackman, G.; Amaudruz, P.; Padula, F.; Ienzi, C.; Santorelli, R.; Bayo, A.; Bonivento, W.M.; Hockin, G.; Desages, F.A.; Scapparone, E.; Viel, S.; Kittmer, A.; Gobui, R.; Elliott, E.; Viviani, L.; Croci, G.; Druszkiewicz, E.; Annovi, A.; Macdonald, M.; Fricbergs, C.; Devoto, A.; Giacomelli, L.; Goeldi, D.; Biagini, D.; Farina, D.; Zambrano, V.; Stringari, P.; Guetre, E.; Bombarda, A.; Foti, G.; Bouchard, M.; Lomonaco, T.; Ford, R.; Westerdale, S.; Reed, D.; Cudmore, S.; Maharaj, R.; Bonfanti, S.; Bicelli, S.; Ippolito, V.; Franco, D.; Shi, A.; Pellegrino, C.; Beschi, M.; Camozzi, M.; Stenzler, A.; Migalla, R.; Kowalkowski, J.; Patel, K.; Trask, D.; Meazzi, E.; Dossi, M.; Scorza, S.; Mapelli, C.; Brice, S.; Ortiz De Solorzano, A.; Pallavicini, M.; Paterno, M.; Pocar, A.; Tseng, J.; Wood, D.; Finocchiaro, G.; Takeuchi, L.; Camozzi, L.; Razeto, A.; Sansoucy, E.; Jillings, C.; Celano, B.; Garcia Abia, P.; Yue, S.; Leblond, G.; Li, X.; Gargantini, A.; De Ruiter, J.; Smith, B.; Hersak, G.; Ianni, A.; Rigamonti, D.; Bagger, J.; Putignano, O.; Hadden, T.; Renshaw, A.; Lim, C.; Bell, B.; Tseng, L.; Smith, N.J.T.; Wang, M.H.L.S.; Caravati, M.; Manni, S.; Massacret, N.; Walter, D.; Batignani, G.; Rizzi, A.; Razeti, M.; Crippa, C.; Constable, M.; Di Francesco, F.; King, M.; Visioli, A.; Dal Molin, A.; Guescini, F.; Liimatainen, P.; Charette, C.; Skensved, P.; Golf, F.; Straubel, C.; Rode, J.; Yates, D.; Gramellini, E.; Palumbo, I.; Lubna, R.; Panontin, E.; Bishop, D.; Thomas, E.; Refsgaard, J.; Back, S.; Carlini, M.; Shawyer, S.; Krücken, R.; Del Tutto, M.; Cogliati, G.; Hessey, N.; Noble, A.J.; Kim, E.; Pelliccione, P.; Calvo-Mozota, J.M.; Capra, A.; Alessi, E.; Settimo, M.; Tardocchi, M.; Ratti, C.; Di Guardo, C.; Laclaustra, M.; Norrick, A.; King, S.; Parmeggiano, L.; Boccali, T.; Girma, T.; Natzke, C.R.; Tartaglia, R.; Lindner, T.; Raaf, J.L.; Velghe, B.; Lukhanin, G.A.; Prelz, F.; Muraro, A.; Tacchino, S.; Mountaniol, M.; Pesudo, V.; Savarese, C.; Duma, C.; Vedia, V.; Kuula, S.; Lennarz, A.; Giarratana, L.S.; Vonica, D.; Monzani, G.; McClurg, P.; Cela Ruiz, J.M.; Shaw, B.; Suchenek, M.; Moretti, C.; Kushoro, M.; Tosatti, L.M.; Sandoval, A.; Sur, B.

doi:10.1063/5.0044445

000109516 001__ 109516
000109516 005__ 20230519145621.0
000109516 0247_ $$2doi$$a10.1063/5.0044445
000109516 0248_ $$2sideral$$a126319
000109516 037__ $$aART-2021-126319
000109516 041__ $$aeng
000109516 100__ $$aAbba, A.
000109516 245__ $$aThe novel Mechanical Ventilator Milano for the COVID-19 pandemic
000109516 260__ $$c2021
000109516 5060_ $$aAccess copy available to the general public$$fUnrestricted
000109516 5203_ $$aThis paper presents the Mechanical Ventilator Milano (MVM), a novel intensive therapy mechanical ventilator designed for rapid, large-scale, low-cost production for the COVID-19 pandemic. Free of moving mechanical parts and requiring only a source of compressed oxygen and medical air to operate, the MVM is designed to support the long-term invasive ventilation often required for COVID-19 patients and operates in pressure-regulated ventilation modes, which minimize the risk of furthering lung trauma. The MVM was extensively tested against ISO standards in the laboratory using a breathing simulator, with good agreement between input and measured breathing parameters and performing correctly in response to fault conditions and stability tests. The MVM has obtained Emergency Use Authorization by U.S. Food and Drug Administration (FDA) for use in healthcare settings during the COVID-19 pandemic and Health Canada Medical Device Authorization for Importation or Sale, under Interim Order for Use in Relation to COVID-19. Following these certifications, mass production is ongoing and distribution is under way in several countries. The MVM was designed, tested, prepared for certification, and mass produced in the space of a few months by a unique collaboration of respiratory healthcare professionals and experimental physicists, working with industrial partners, and is an excellent ventilator candidate for this pandemic anywhere in the world.
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000109516 590__ $$a4.98$$b2021
000109516 592__ $$a1.189$$b2021
000109516 594__ $$a5.7$$b2021
000109516 591__ $$aPHYSICS, FLUIDS & PLASMAS$$b2 / 34 = 0.059$$c2021$$dQ1$$eT1
000109516 593__ $$aComputational Mechanics$$c2021$$dQ1
000109516 591__ $$aMECHANICS$$b18 / 138 = 0.13$$c2021$$dQ1$$eT1
000109516 593__ $$aMechanics of Materials$$c2021$$dQ1
000109516 593__ $$aMechanical Engineering$$c2021$$dQ1
000109516 593__ $$aCondensed Matter Physics$$c2021$$dQ1
000109516 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
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000109516 700__ $$aAgnes, P.
000109516 700__ $$aAlessi, E.
000109516 700__ $$aAmaudruz, P.
000109516 700__ $$aAnnovi, A.
000109516 700__ $$aDesages, F.A.
000109516 700__ $$aBack, S.
000109516 700__ $$aBadia, C.
000109516 700__ $$aBagger, J.
000109516 700__ $$aBasile, V.
000109516 700__ $$aBatignani, G.
000109516 700__ $$aBayo, A.
000109516 700__ $$aBell, B.
000109516 700__ $$aBeschi, M.
000109516 700__ $$aBiagini, D.
000109516 700__ $$aBianchi, G.
000109516 700__ $$aBicelli, S.
000109516 700__ $$aBishop, D.
000109516 700__ $$aBoccali, T.
000109516 700__ $$aBombarda, A.
000109516 700__ $$aBonfanti, S.
000109516 700__ $$aBonivento, W.M.
000109516 700__ $$aBouchard, M.
000109516 700__ $$aBreviario, M.
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000109516 700__ $$aBrown, R.
000109516 700__ $$aCalvo-Mozota, J.M.
000109516 700__ $$aCamozzi, L.
000109516 700__ $$aCamozzi, M.
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000109516 700__ $$aCaravati, M.
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000109516 700__ $$aCeccanti, A.
000109516 700__ $$aCelano, B.
000109516 700__ $$aCela Ruiz, J.M.
000109516 700__ $$aCharette, C.
000109516 700__ $$aCogliati, G.
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000109516 700__ $$aDahl, C.E.
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000109516 700__ $$aDi Guardo, C.
000109516 700__ $$aD'Avenio, G.
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000109516 700__ $$aDel Tutto, M.
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000109516 700__ $$aDiaz Gomez Maqueo, P.
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000109516 700__ $$aDruszkiewicz, E.
000109516 700__ $$aDuma, C.
000109516 700__ $$aElliott, E.
000109516 700__ $$aFarina, D.
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000109516 700__ $$aGargantini, A.
000109516 700__ $$aGiacomelli, L.
000109516 700__ $$aGiacomini, F.
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000109516 700__ $$aHeavey, A.
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000109516 700__ $$aHockin, G.
000109516 700__ $$aHudson, K.
000109516 700__ $$aIanni, A.
000109516 700__ $$aIenzi, C.
000109516 700__ $$aIppolito, V.
000109516 700__ $$aJames, C.C.
000109516 700__ $$aJillings, C.
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000109516 700__ $$aKhan, S.
000109516 700__ $$aKim, E.
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000109516 700__ $$aPadula, F.
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000109516 700__ $$aScorza, S.
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000109516 7102_ $$12004$$2X$$aUniversidad de Zaragoza$$bDpto. Física Teórica$$cÁrea Técnica. Lab. y Talleres
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