Treatment patterns and outcomes among nontransplant newly diagnosed multiple myeloma patients in Spain

Hernández-Rivas, J.-A. ; Arnao, M. ; Arguiñano Pérez, J.M. ; Rubio, A. (Universidad de Zaragoza) ; González García, E. ; De Miguel, D. ; Cherepanov, D. ; Romanus, D. ; Verleger, K. ; Johnson, C. ; Corman, S.L. ; Grande, M. ; Pérez Persona, E.

Resumen: Aim: To describe treatment patterns and outcomes in nontransplant newly diagnosed multiple myeloma (NDMM) patients in Spain. Methods: This retrospective study included two cohorts of NDMM patients diagnosed between 1 January 2012 to 31 December 2013 and 1 April 2016 to 31 March 2017. Results: Among 113 patients, proteasome inhibitor (PI) + alkylator combinations (49%) and PI-based regimens without an alkylator (30%) were the most common first-line (1L) therapies. Use of PI + immunomodulatory drug-based regimens increased between the cohorts; PI-based regimens without an alkylator/immunomodulatory drug decreased. Use of 1L oral regimens was low but increased over time; use of maintenance therapy was low across both periods. Median 1L duration of treatment was 6.9 months. Conclusion: Short 1L duration of treatment and low use of 1L oral regimens and maintenance therapy highlight unmet needs in NDMM. © 2021 The Authors.

Idioma: Inglés

DOI: 10.2217/fon-2021-0301

Año: 2021

Publicado en: FUTURE ONCOLOGY 17, 26 (2021), 3465-3476
ISSN: 1479-6694

Factor impacto JCR: 3.674 (2021)

Categ. JCR: ONCOLOGY rank: 149 / 245 = 0.608 (2021) - Q3 - T2

Factor impacto CITESCORE: 4.9 - Medicine (Q2) - Biochemistry, Genetics and Molecular Biology (Q2)

Factor impacto SCIMAGO: 0.836 - Oncology (Q2) - Medicine (miscellaneous) (Q2)

Tipo y forma: Comunicación congreso (Versión definitiva)

Área (Departamento): Área Dermatología (Dpto. Medicina, Psiqu. y Derm.)