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> Clinical and demographic factors in endometrial and ovary carcinoma: Synchronous carcinoma vs stage IIIA endometrial carcinoma
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Clinical and demographic factors in endometrial and ovary carcinoma: Synchronous carcinoma vs stage IIIA endometrial carcinoma
Baquedano Mainar, Laura
(Universidad de Zaragoza)
;
Navarro Sierra, Javier
;
Alvárez Sarrado, Leticia
;
José Gutiérrez, Yasmina
;
Lamarca Ballestero, Marta
;
Rubio Cuesta, Patricia
;
Ruiz Peña, Ana C.
;
Espiau Romera, Andrea
(Universidad de Zaragoza)
Resumen:
Objective: To compare pre-surgical demographic and clinical factors and preoperative serum tumor marker values of patients with endometrial and ovarian synchronous carcinoma with those diagnosed with endometrial carcinoma with metastatic ovarian involvement (FIGO stage IIIA). Methods: A retrospective observational study including patients with endometrial and ovarian malignant tumors that were treated at Miguel Servet University Hospital, Zaragoza, Spain, since January 2000 to June 2020. All pathologic specimens were reviewed by two pathologists specialized in gynecological oncology. Results: Overall, 51 patients were included. 24 cases of them, were endometrial and ovarian synchronous primary carcinomas and the remaining 27 cases were endometrial tumors with adnexa. Parity, personal and family oncological history, arterial hypertension, diabetes, dyslipidemia, obesity and the prior use of hormone replacement therapy did not show significant differences between both groups. Age (p = 0.002), menopausal status (p = 0.029), abnormal uterine bleeding (p = 0.001), Ca 12.5 preoperative serum level (p = 0.038) and Ca 19.9 preoperative serum level (0.028) were factors with significant differences between both groups. In multivariate analysis, only abnormal uterine bleeding and Ca 19.9 values were independents factors. Conclusions: The presence of abnormal uterine bleeding and Ca 19.9 preoperative serum level could guide the clinician in the preoperative differential diagnosis between endometrial cancer with ovarian involvement and endometrial and ovarian synchronous carcinoma. © 2021 The Author(s).
Idioma:
Inglés
DOI:
10.31083/j.ejgo4204099
Año:
2021
Publicado en:
EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
42, 4 (2021), 643-648
ISSN:
0392-2936
Factor impacto JCR:
0.255 (2021)
Categ. JCR:
ONCOLOGY
rank: 243 / 245 = 0.992
(2021)
- Q4
- T3
Categ. JCR:
OBSTETRICS & GYNECOLOGY
rank: 83 / 85 = 0.976
(2021)
- Q4
- T3
Factor impacto SCIMAGO:
0.0 -
Oncology
-
Obstetrics and Gynecology
Tipo y forma:
Artículo (Versión definitiva)
Área (Departamento):
Área Obstetricia y Ginecología
(
Dpto. Cirugía
)
Debe reconocer adecuadamente la autoría, proporcionar un enlace a la licencia e indicar si se han realizado cambios. Puede hacerlo de cualquier manera razonable, pero no de una manera que sugiera que tiene el apoyo del licenciador o lo recibe por el uso que hace.
Exportado de SIDERAL (2023-05-18-16:00:48)
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Registro creado el 2022-08-17, última modificación el 2023-05-19
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