Macular Choroidal Thickness: Evaluation of Variability among Measurements and Assessment of Predictive Value of Glaucomatous Visual Field Damag

Marenco, M. ; Rissotto, F. ; Palamini, A. ; Cutolo, C. A. ; Agosto, G. ; Ferreras Amez, A. (Universidad de Zaragoza) ; Traverso, C. E. ; Iester, M.

Resumen: Introduction: This study aimed to investigate the relationship between the choroidal circulation and glaucoma, assessing macular choroidal thickness (MCT) as a predictive value of glaucomatous visual field damage. Methods: Twenty primary open-angle glaucoma patients were recruited. Patients underwent 2 SS-OCT scans: one with DRI OCT (Topcon) and the other with PLEX Elite 9000 (Zeiss). Standard OCT parameters were acquired by DRI OCT, while MCT was manually measured in 5 points on Plex ELITE 9000 images. The relationship among MCT, standard OCT parameters, and visual field indices was evaluated. Pearson''s r correlation was calculated to evaluate these relationships. Reproducibility of measurements was analyzed. Results: MCT measurements showed a good intra- and interobserver repeatability. A negative correlation appeared between MCT and BMI (r = -0.518, p = 0.023). Mean deviation showed a statistically significant correlation with MCT measured at subfoveal and at 1, 000 µm nasally (r = 0.50, p = 0.03, and r = 0.52, p = 0.023). A correlation was found between the 2 MCT (Zeiss vs. Topcon) measurements and between MCT and peripapillary choroidal thickness (r = 0.944 and r = 0.740, p < 0.001, respectively). Conclusions: A good intra- and interobserver reproducibility was found. MCT showed a weak predictive value of glaucomatous visual field damage. A significant correlation was found between MCT and BMI. © 2021

Idioma: Inglés

DOI: 10.1159/000520834

Año: 2022

Publicado en: OPHTHALMIC RESEARCH 65, 4 (2022), 417-424
ISSN: 0030-3747

Factor impacto JCR: 2.1 (2022)

Categ. JCR: OPHTHALMOLOGY rank: 35 / 62 = 0.565 (2022) - Q3 - T2

Factor impacto CITESCORE: 4.6 - Neuroscience (Q2) - Medicine (Q2)

Factor impacto SCIMAGO: 0.708 - Medicine (miscellaneous) (Q2) - Sensory Systems (Q2) - Ophthalmology (Q2) - Cellular and Molecular Neuroscience (Q3)

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Oftalmología (Dpto. Cirugía)