Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry

Díez-Manglano, Jesús (Universidad de Zaragoza) ; Solís Marquínez, Marta Nataya ; Álvarez García, Andrea ; Alcalá-Rivera, Nicolás ; Maderuelo Riesco, Irene ; Gericó Aseguinolaza, Martín ; Beato Pérez, José Luis ; Méndez Bailón, Manuel ; Labirua-Iturburu Ruiz, Ane Elbire ; García Gómez, Miriam ; Martínez Cilleros, Carmen ; Pesqueira Fontan, Paula María ; Abella Vázquez, Lucy ; Blázquez Encinar, Julio César ; Boixeda, Ramón ; Gil Sánchez, Ricardo ; Peña Fernández, Andrés de la ; Loureiro Amigo, Jose ; Escobar Sevilla, Joaquín ; Guzmán García, Marcos ; Martín Escalante, María Dolores ; Magallanes Gamboa, Jeffrey Oskar ; Martínez González, Ángel Luis ; Lumbreras Bermejo, Carlos ; Antón Santos, Juan Miguel ; Agudo de Blas, Paloma ; Arévalo Cañas, Coral ; Ayuso, Blanca ; Bascuñana Morejón, José ; Carnevali Frías, María ; Cossio Tejido, Santiago ; Miguel Campo, Borja de ; Díaz Pedroche, Carmen ; Díaz Simon, Raquel ; García Reyne, Ana ; Jorge Huerta, Lucía ; Lalueza Blanco, Antonio ; Laureiro Gonzalo, Jaime ; Maestro de la Calle, Guillermo ; Otero Perpiña, Bárbara ; Paredes Ruiz, Diana ; Sánchez Fernández, Marcos ; Tejada Montes, Javier ; Abarca Casas, Laura ; Alejandre de Oña, Álvaro ; Alonso Beato, Rubén ; Alonso Gonzalo, Leyre ; Alonso Muñoz, Jaime ; Amodeo Oblitas, Christian Mario ; Ausín García, Cristina ; Bacete Cebrián, Marta ; Baltasar Corral, Jesús ; Barrientos Guerrero, María ; Bendala Estrada, Alejandro ; Calderón Moreno, María ; Carrascosa Fernández, Paula ; Carrillo, Raquel ; Castañeda Pérez, Sabela ; Cervilla Muñoz, Eva ; Chacón Moreno, Agustín Diego ; Cuenca Carvajal, María Carmen ; Santos, Sergio de ; Enríquez Gómez, Andrés ; Fernández Carracero, Eduardo ; Ferreiro-Mazón Jenaro, María Mercedes ; Galeano Valle, Francisco ; García, Alejandra ; García Fernández-Bravo, Irene ; García Leoni, María Eugenia ; Gómez Antúnez, María ; González San Narciso, Candela ; Alexander Gurjian, Anthony ; Jiménez Ibáñez, Lorena ; Lavilla Olleros, Cristina ; Llamazares Mendo, Cristina ; Luis García, Sara ; Mato Jimeno, Víctor ; Millán Nohales, Clara ; Millán Nuñez-Cortés, Jesús ; Moragón Ledesma, Sergio ; Muiño Miguez, Antonio ; Muñoz Delgado, Cecilia ; Ordieres Ortega, Lucía ; Pardo Sánchez, Susana ; Parra Virto, Alejandro ; Pérez Sanz, María Teresa ; Pinilla Llorente, Blanca ; Piqueras Ruiz, Sandra ; Soria Fernández-Llamazares, Guillermo ; Toledano Macías, María ; Toledo Samaniego, Neera ; Torres do Rego, Ana ; Villalba García, María Victoria ; Villarreal, Gracia ; Zurita Etayo, María ; Corbella, Xavier ; Montero, Abelardo ; Mora-Luján, José María ; Sáez Méndez, Lourdes ; Álvarez Troncoso, Jorge ; Arnalich Fernández, Francisco ; Blanco Quintana, Francisco ; Busca Arenzana, Carmen ; Carrasco Molina, Sergio ; Castellano Candalija, Aranzazu ; Daroca Bengoa, Germán ; Gea Grela, Alejandro de ; Lorenzo Hernández, Alicia de ; Díez Vidal, Alejandro ; Fernández Capitán, Carmen ; García Iglesias, María Francisca ; González Muñoz, Borja ; Herrero Gil, Carmen Rosario ; Herrero Martínez, Juan María ; Hontañón, Víctor ; Jaras Hernández, María Jesús ; Lahoz, Carlos ; Marcelo Calvo, Cristina ; Sáez Comet, Luis (Universidad de Zaragoza)

Resumen: Aim To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). Methods Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and treatment data on patients hospitalised with COVID-19 in Spain. Patients aged 20-65 years were selected. A multivariate logistic regression model was performed to identify factors associated with mortality. Results As of 22 May 2020, 4393 patients were included, of whom 419 (9.5%) were HCW. Median (interquartile range) age of HCW was 52 (15) years and 62.4% were women. Prevalence of comorbidities and severe radiological findings upon admission were less frequent in HCW. There were no difference in need of respiratory support and admission to intensive care unit, but occurrence of sepsis and in-hospital mortality was lower in HCW (1.7% vs. 3.9%; p = 0.024 and 0.7% vs. 4.8%; p<0.001 respectively). Age, male sex and comorbidity, were independently associated with higher in-hospital mortality and healthcare working with lower mortality (OR 0.211, 95%CI 0.067-0.667, p = 0.008). 30-days survival was higher in HCW (0.968 vs. 0.851 p<0.001). Conclusions Hospitalized COVID-19 HCW had fewer comorbidities and a better prognosis than NHCW. Our results suggest that professional exposure to COVID-19 in HCW does not carry more clinical severity nor mortality.

Idioma: Inglés

DOI: 10.1371/journal.pone.0247422

Año: 2021

Publicado en: PLoS ONE 16, 2 February (2021), e0247422 [10 pp.]
ISSN: 1932-6203

Factor impacto JCR: 3.752 (2021)

Categ. JCR: MULTIDISCIPLINARY SCIENCES rank: 29 / 74 = 0.392 (2021) - Q2 - T2

Factor impacto SCIMAGO: 0.852 - Multidisciplinary (Q1)

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)