Comparative study of the use of Doxycycline and Oxytetracycline to treat Anaplasmosis in fattening lambss

Lacasta, D. (Universidad de Zaragoza) ; Ruiz, H. (Universidad de Zaragoza) ; Ortín, A. (Universidad de Zaragoza) ; Villanueva-Saz, S. (Universidad de Zaragoza) ; Estrada-Peña, A. (Universidad de Zaragoza) ; González, J. M. (Universidad de Zaragoza) ; Ramos, J. J. (Universidad de Zaragoza) ; Ferrer, L. M. (Universidad de Zaragoza) ; Benito, A. Á. ; Labanda, R. ; Malo, C. ; Verde, M. T. (Universidad de Zaragoza) ; Fernández, A. (Universidad de Zaragoza) ; Ruiz de Arcaute, M. (Universidad de Zaragoza)

Resumen: Lamb icteric carcasses condemnation due to Anaplasma ovis is causing relevant economic losses. A comparative study was developed on the effects of different antibiotics to treat ovine anaplasmosis in fattening lambs. A total of 100 A. ovis naturally infected lambs were selected and randomly divided into four groups of 25 lambs: Group ID, treated with injectable doxycycline; Group OD, oral doxycycline; Group O, injectable oxytetracycline; and Group C, untreated animals for the control group. Clinical, haematological, and molecular analyses were performed before the treatment and 12 and 45 days after the beginning of the treatments, and carcass condemnation was followed after slaughter. The A. ovis bacterial load was high before the treatments in the four groups and decreased significantly 45 days after treatment in the ID and O Groups (p < 0.001). The parameters that were related to haemolysis showed similar results. At the abattoir, 15 out of the 47 examined carcasses were condemned; 7 of C Group, 6 of OD Group, 2 of O Group, and 0 of ID Group. It can be concluded that injectable doxycycline and oxytetracycline significantly reduce A. ovis bacterial load in blood and carcass condemnation at the abattoir. Further studies are needed in order to confirm these encouraging findings.

Idioma: Inglés

DOI: 10.3390/ani12172279

Año: 2022

Publicado en: Animals 12, 17 (2022), 2279[12 pp.]
ISSN: 2076-2615

Factor impacto JCR: 3.0 (2022)

Categ. JCR: VETERINARY SCIENCES rank: 13 / 144 = 0.09 (2022) - Q1 - T1
Categ. JCR: AGRICULTURE, DAIRY & ANIMAL SCIENCE rank: 12 / 62 = 0.194 (2022) - Q1 - T1

Factor impacto CITESCORE: 4.2 - Veterinary (Q1) - Agricultural and Biological Sciences (Q2)

Factor impacto SCIMAGO: 0.684 - Veterinary (miscellaneous) (Q1) - Animal Science and Zoology (Q1)

Financiación: info:eu-repo/grantAgreement/ES/DGA/A15-20R

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Sanidad Animal (Dpto. Patología Animal)
Área (Departamento): Área Medicina y Cirugía Animal (Dpto. Patología Animal)