Bone turnover alterations after completing a multistage ultra-trail: a case study

Castellar Otín, Carlos (Universidad de Zaragoza) ; Lecina, Miguel ; Pradas, Francisco (Universidad de Zaragoza)

Resumen: A series of case studies aimed to assess bone and stress fractures in a 768-km ultra-trail race for 11 days. Four nonprofessional male athletes completed the event without diagnosing any stress fracture. Bone turnover markers (osteocalcin (OC), serum C-terminal cross-linking telopeptide of type I collagen (CTX), bone-specific alkaline phosphatase (BALP), and serum turnover calcium (Ca2+)) were assessed before (pre) and after the race (post) and on days two and nine during the recovery period (rec2 and rec9), respectively. Results showed: post-pre-OC = -45.78%, BALP = -61.74%, CTX = +37.28% and Ca2+ = -3.60%. At rec2 and rec9, the four parameters did not return to their pre-run levels: OC, -48.31%; BALP, -61.66%; CTX, +11.93% and Ca2+, -3.38%; and OC = -25.12%, BALP = -54.65%, CTX = +93.41% and Ca2+ = +3.15%), respectively. Our results indicated that the ultra-trail race induced several changes in bone turnover markers, uncoupling of bone metabolism, increased bone resorption: OC and BALP and suppressed bone formation: CTX and Ca2+. Bone turnover markers can help determine the response of bone to extreme effort and might also help predict the risk of stress fractures. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Idioma: Inglés

DOI: 10.3390/healthcare10050798

Año: 2022

Publicado en: Healthcare (Switzerland) 10, 5 (2022), 798 [10 pp.]
ISSN: 2227-9032

Factor impacto JCR: 2.8 (2022)

Categ. JCR: HEALTH POLICY & SERVICES rank: 43 / 87 = 0.494 (2022) - Q2 - T2
Categ. JCR: HEALTH CARE SCIENCES & SERVICES rank: 57 / 106 = 0.538 (2022) - Q3 - T2

Factor impacto CITESCORE: 2.7 - Health Professions (Q2) - Medicine (Q3)

Factor impacto SCIMAGO: 0.55 - Health Policy (Q2) - Leadership and Management (Q2) - Health Informatics (Q3) - Health Information Management (Q3)

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Didáctica Expres.Corporal (Dpto. Expres.Music.Plást.Corp.)