Dose–response association of handgrip strength and risk of depression: a longitudinal study of 115 601 older adults from 24 countries

López-Bueno, Rubén ; Calatayud, J. ; Andersen, L.L. ; Casaña, J. ; Koyanagi, A. ; Del Pozo Cruz, B. ; Smith, L.

Resumen: Background: Prior research has solely focused on the association between handgrip strength and risk of depression in single countries or general populations, but more knowledge is required from wider-spread cohorts and target populations. Aims: This study aimed to investigate the association between handgrip strength and risk of depression using repeated measures in adults aged 50 years and over. Method: Data on handgrip strength and risk of depression were retrieved from the Survey of Health, Ageing and Retirement in Europe (SHARE) waves 1, 2, 4, 5, 6 and 7, using a hand dynamometer (Smedley, S Dynamometer, TTM) and the EURO-D 12-item scale, respectively. Time-varying exposure and covariates were modelled using both Cox regression and restricted cubic splines. Results: A total of 115 601 participants (mean age 64.3 years (s.d. = 9.9), 54.3% women) were followed-up for a median of 7.3 years (interquartile range: 3.9–11.8) and 792 459 person-years. During this period, 30 208 (26.1%) participants experienced a risk of depression. When modelled as a continuous variable, we observed an inverse significant association for each kg increase of handgrip strength and depression up to 40 kg in men and up to 27 kg in women. Conclusions: Being physically strong may serve as a preventive factor for depression in older adults, but this is limited up to a maximum specific threshold for men and women.

Idioma: Inglés

DOI: 10.1192/bjp.2022.178

Año: 2023

Publicado en: BRITISH JOURNAL OF PSYCHIATRY 222, 3 (2023), 135-142
ISSN: 0007-1250

Factor impacto JCR: 8.8 (2023)

Categ. JCR: PSYCHIATRY rank: 10 / 279 = 0.036 (2023) - Q1 - T1
Categ. JCR: PSYCHIATRY rank: 10 / 279 = 0.036 (2023) - Q1 - T1

Factor impacto CITESCORE: 13.7 - Psychiatry and Mental Health (Q1)

Factor impacto SCIMAGO: 2.717 - Psychiatry and Mental Health (Q1) - Medicine (miscellaneous) (Q1)

Financiación: info:eu-repo/grantAgreement/EC/FP6/28812/EU/Employment and health at 50+: a life history approach to european welfare state interventions/SHARELIFE
Financiación: info:eu-repo/grantAgreement/EC/FP6/28857/EU/Toolbox for Improving the Comparability of Cross-National Survey Data with Applications to SHARE/COMPARE
Financiación: info:eu-repo/grantAgreement/EC/FP6/62193/EU/Survey of Health, Ageing and Retirement in Europe: Integrating Activities to Access the Time Dimension and to Enlarge the Cross-national Dimension/SHARE-I3
Financiación: info:eu-repo/grantAgreement/EC/FP7/211909/EU/Upgrading the Survey of Health, Ageing and Retirement in Europe – preparatory phase/SHARE-PREP
Financiación: info:eu-repo/grantAgreement/EC/FP7/227822/EU/Longitudinal Enhancement and Access imProvement of the SHARE infrastructure/SHARE_LEAP
Financiación: info:eu-repo/grantAgreement/EC/FP7/261982/EU/Multinational Advancement of Research Infrastructures on Ageing/SHARE_M4
Financiación: info:eu-repo/grantAgreement/EC/FP7/283646/EU/Data Service Infrastructure for the Social Sciences and Humanities/DASISH
Financiación: info:eu-repo/grantAgreement/EC/HS/QLK6-CT-2001-00360/EU/Survey on health, ageing and retirement in europe (SHARE)/SHARE
Financiación: info:eu-repo/grantAgreement/EC/H2020/654221/EU/Synergies for Europe's Research Infrastructures in the Social Sciences/SERISS
Financiación: info:eu-repo/grantAgreement/EC/H2020/676536/EU/Achieving world-class standards in all SHARE countries/SHARE-DEV3
Financiación: info:eu-repo/grantAgreement/EC/H2020/823782/EU/Social Sciences & Humanities Open Cloud/SSHOC
Financiación: info:eu-repo/grantAgreement/EC/H2020/870628/EU/Cohesion in further developing and innovating SHARE across all 28 member countries/SHARE-COHESION

Tipo y forma: Artículo (Versión definitiva)