Analgesics and ASH medications in workers increase the risk of disability pension and mortality: prospective cohort

Andersen, Lars Louis ; Vinstrup, Jonas ; Calatayud, Joaquín ; López-Bueno, Rubén ; Clausen, Thomas ; Manniche, Claus

Resumen: Background
Relying on medication for musculoskeletal and mental disorders are common, but may have long-term consequences. This study investigates whether use of analgesics and anxiolytic/sedative/hypnotic (ASH) medication increases the risk of disability pension and mortality.
Methods
After completing a survey in 2005, 7773 female eldercare workers were followed for 11 years in a national register. We estimated hazard ratios (HRs) for disability pension and mortality from using analgesics and ASH.
Results
During follow-up, 10.3% obtained disability pension and 2.4% died. For use of analgesics, a frequency-response association for the risk of disability pension existed with HR’s (95% confidence interval) of 1.30 (1.07–1.57), 2.00 (1.62–2.46) and 3.47 (2.69–4.47) for monthly, weekly and daily use, respectively. For ASH, an increased risk of disability pension also existed (HR’s between 1.51 and 1.64). For mortality risk, only daily use of analgesics and ASH remained significant. Population attributable fractions of analgesics and ASH, respectively, were 30% and 3% for disability pension and 5% and 3% for mortality.
Conclusions
Frequent use of analgesics and ASH medication in workers increase the risk of disability pension and early death. Better management of musculoskeletal and mental health conditions, without excessive medication use, is necessary.

Idioma: Inglés

DOI: 10.1093/eurpub/ckad064

Año: 2023

Publicado en: European Journal of Public Health 33, 4 (2023), 601–605
ISSN: 1101-1262

Factor impacto JCR: 3.7 (2023)

Categ. JCR: PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH rank: 73 / 408 = 0.179 (2023) - Q1 - T1
Categ. JCR: PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH rank: 73 / 408 = 0.179 (2023) - Q1 - T1

Factor impacto CITESCORE: 5.6 - Public Health, Environmental and Occupational Health (Q1)

Factor impacto SCIMAGO: 1.078 - Public Health, Environmental and Occupational Health (Q1)

Tipo y forma: Artículo (Versión definitiva)