000036781 001__ 36781
000036781 005__ 20170831220326.0
000036781 037__ $$aTAZ-TFM-2015-1094
000036781 041__ $$aeng
000036781 1001_ $$aRuiz Rincón, Silvia
000036781 24500 $$aFormation and characterization of model cell membranes and their interaction with Magnetic Nanoparticles
000036781 260__ $$aZaragoza$$bUniversidad de Zaragoza$$c2015
000036781 506__ $$aby-nc-sa$$bCreative Commons$$c3.0$$uhttp://creativecommons.org/licenses/by-nc-sa/3.0/
000036781 520__ $$aIn this final master project model cell membranes of a mixture of 1, 2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and cholesterol were transferred onto mica substrates by Langmuir-Blodgett technique (LB) to mimic a real cell membrane. The high quality and chemical structure of the monolayers formed were confirmed by means of Atomic Force Microscopy (AFM) imaging and Contact Angle measurements. A study of the stability of the monolayer in liquid media considering the amphiphilic nature of the compounds was carried out, observing as the monolayer re-assembled into bilayer. This behaviour was explained by means of Force Spectroscopy (FS) studies with a noticeable increase in the breakthrough force values. Furthermore, the deposition of MNPs onto monolayer was carried out by LB in a successful way obtaining a well-covered distribution of MNPs with the final purpose of study the membrane response when it is exposed to alternating magnetic fields (Hyperthermia).
000036781 521__ $$aMáster Universitario en Materiales Nanoestructurados para Aplicaciones Nanotecnológicas (Nanostructured Materials for Nanotechnology Applications)
000036781 540__ $$aDerechos regulados por licencia Creative Commons
000036781 700__ $$aCea Mingueza, Pilar$$edir.
000036781 700__ $$aMartínez de la Fuente, Jesús$$edir.
000036781 7102_ $$aUniversidad de Zaragoza$$bQuímica Física$$cQuímica Física
000036781 8560_ $$f591175@celes.unizar.es
000036781 8564_ $$s2448926$$uhttps://zaguan.unizar.es/record/36781/files/TAZ-TFM-2015-1094.pdf$$yMemoria (eng)
000036781 8564_ $$s498296$$uhttps://zaguan.unizar.es/record/36781/files/TAZ-TFM-2015-1094_ANE.pdf$$yAnexos (eng)
000036781 909CO $$ooai:zaguan.unizar.es:36781$$pdriver$$ptrabajos-fin-master
000036781 950__ $$a
000036781 951__ $$adeposita:2016-01-15
000036781 980__ $$aTAZ$$bTFM$$cCIEN