000048603 001__ 48603
000048603 005__ 20200221144112.0
000048603 0247_ $$2doi$$a10.1007/s00198-015-3232-9
000048603 0248_ $$2sideral$$a92303
000048603 037__ $$aART-2016-92303
000048603 041__ $$aeng
000048603 100__ $$0(orcid)0000-0001-8500-1667$$aMatute-Llorente, A.$$uUniversidad de Zaragoza
000048603 245__ $$aEffect of whole-body vibration training on bone mass in adolescents with and without Down syndrome: a randomized controlled trial
000048603 260__ $$c2016
000048603 5060_ $$aAccess copy available to the general public$$fUnrestricted
000048603 5203_ $$aSummary: Whole-body vibration training (WBV) attracts great interest as osteoporosis prevention strategy. Twenty-six adolescents with and without Down syndrome (DS) (13 DS//12–18 years) performed 20 weeks of WBV. The results indicate that WBV seems to provoke a lesser response in adolescents with DS than in those without DS. Introduction: This study aims to observe the differences between adolescents with and without DS in the effects of 20 weeks of WBV training, on bone mineral content (BMC) and density (BMD). Methods: Twenty-six adolescents (13 DS//12–18 years) were measured with dual-energy X-ray absorptiometry before and after the intervention (3/week, 10 repetitions (30–60 s) and 1-min rest, frequency 25–30 Hz and peak-to-peak displacement of 2 mm (peak acceleration 2.5–3.6 g)). Both, an intention-to-treat (ITT) analysis designed to assess the effects on bone mass and a per-protocol analysis, designed to compare poor and high compliers, were performed. Results: The ITT analysis revealed significant increases in all BMC and BMD parameters (dz = 0.66 to 1.64//all p < 0.05) in the non-DS group, whilst DS group improved whole-body, subtotal (whole-body less head), upper limbs (ULIMBS), pelvis, lower limbs (LLIMBS) and spine BMC (dz = 0.75 to 1.76//all p < 0.05) and subtotal, pelvis, LLIMBS and spine BMD (dz = 0.73 to 1.28//all p < 0.05). Significantly greater increases were evident in the absolute and percent changes of the non-DS group over DS group (d = 0.88 to 3.85//all p < 0.05). ULIMBS BMD showed a tendency towards an interaction (f = 0.41 and p = 0.086) with higher increase for non-DS group. When a per-protocol analysis was considered, high-complier adolescents had 8.1 versus 5.3 % of gains in the spine BMC over poor-complier adolescents (d = 0.93//p < 0.05). Conclusions: Twenty weeks of WBV training may improve BMC and BMD in clinically relevant skeletal sites in both groups. Nevertheless, this type of training seems to provoke a lesser response in adolescents with DS than in those without DS.
000048603 536__ $$9info:eu-repo/grantAgreement/ES/MICINN/DEP2009-09183$$9info:eu-repo/grantAgreement/ES/MEC/AP-2012-02854
000048603 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000048603 590__ $$a3.591$$b2016
000048603 591__ $$aENDOCRINOLOGY & METABOLISM$$b52 / 138 = 0.377$$c2016$$dQ2$$eT2
000048603 592__ $$a1.516$$b2016
000048603 593__ $$aMedicine (miscellaneous)$$c2016$$dQ1
000048603 593__ $$aEndocrinology, Diabetes and Metabolism$$c2016$$dQ1
000048603 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000048603 700__ $$0(orcid)0000-0002-1132-5906$$aGonzález-Agüero, A.$$uUniversidad de Zaragoza
000048603 700__ $$0(orcid)0000-0001-6492-2512$$aGómez-Cabello, A.
000048603 700__ $$aTous-Fajardo, J.
000048603 700__ $$0(orcid)0000-0002-4303-4097$$aVicente-Rodríguez, G.$$uUniversidad de Zaragoza
000048603 700__ $$0(orcid)0000-0002-7215-6931$$aCasajús, J.A.$$uUniversidad de Zaragoza
000048603 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000048603 773__ $$g27,  1 (2016), 187-191$$pOsteoporos. int.$$tOSTEOPOROSIS INTERNATIONAL$$x0937-941X
000048603 8564_ $$s3272319$$uhttps://zaguan.unizar.es/record/48603/files/texto_completo.pdf$$yPostprint
000048603 8564_ $$s84559$$uhttps://zaguan.unizar.es/record/48603/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000048603 909CO $$ooai:zaguan.unizar.es:48603$$particulos$$pdriver
000048603 951__ $$a2020-02-21-13:02:03
000048603 980__ $$aARTICLE