000057087 001__ 57087
000057087 005__ 20200221144258.0
000057087 0247_ $$2doi$$a10.2196/jmir.5695
000057087 0248_ $$2sideral$$a96726
000057087 037__ $$aART-2016-96726
000057087 041__ $$aeng
000057087 100__ $$0(orcid)0000-0001-5677-1662$$aMontero-Marín, J.
000057087 245__ $$aAn internet-based intervention for depression in primary care in Spain: A randomized controlled trial
000057087 260__ $$c2016
000057087 5060_ $$aAccess copy available to the general public$$fUnrestricted
000057087 5203_ $$aBackground: Depression is the most prevalent cause of illness-induced disability worldwide. Face-to-face psychotherapeutic interventions for depression can be challenging, so there is a need for other alternatives that allow these interventions to be offered. One feasible alternative is Internet-based psychological interventions. This is the first randomized controlled trial (RCT) on the effectiveness of an Internet-based intervention on depression in primary health care in Spain. Objective: Our aim was to compare the effectiveness of a low-intensity therapist-guided (LITG) Internet-based program and a completely self-guided (CSG) Internet-based program with improved treatment as usual (iTAU) care for depression. Methods: Multicenter, three-arm, parallel, RCT design, carried out between November 2012 and January 2014, with a follow-up of 15 months. In total, 296 adults from primary care settings in four Spanish regions, with mild or moderate major depression, were randomized to LITG (n=96), CSG (n=98), or iTAU (n=102). Research completers at follow-up were 63.5%. The intervention was Smiling is Fun, an Internet program based on cognitive behavioral therapy. All patients received iTAU by their general practitioners. Moreover, LITG received Smiling is Fun and the possibility of psychotherapeutic support on request by email, whereas CSG received only Smiling is Fun. The main outcome was the Beck Depression Inventory-II at 3 months from baseline. Mixed-effects multilevel analysis for repeated measures were undertaken. Results: There was no benefit for either CSG (B coefficient=-1.15; P=.444)] or LITG (B=-0.71; P=.634)] compared to iTAU, at 3 months. There were differences at 6 months iTAU vs CSG (B=-4.22; P=.007); iTAU vs LITG (B=-4.34; P=.005)] and 15 months iTAU vs CSG (B=-5.10; P=.001); iTAU vs LITG (B=-4.62; P=.002)]. There were no differences between CSG and LITG at any time. Adjusted and intention-to-treat models confirmed these findings. Conclusions: An Internet-based intervention for depression combined with iTAU conferred a benefit over iTAU alone in the Spanish primary health care system.
000057087 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/PI10-01083$$9info:eu-repo/grantAgreement/ES/ISCIII/RD12-0005
000057087 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000057087 590__ $$a5.175$$b2016
000057087 591__ $$aMEDICAL INFORMATICS$$b1 / 23 = 0.043$$c2016$$dQ1$$eT1
000057087 591__ $$aHEALTH CARE SCIENCES & SERVICES$$b4 / 90 = 0.044$$c2016$$dQ1$$eT1
000057087 592__ $$a2.132$$b2016
000057087 593__ $$aHealth Informatics$$c2016$$dQ1
000057087 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000057087 700__ $$aAraya, R.
000057087 700__ $$aPérez-Yus, M.C.
000057087 700__ $$aMayoral, F.
000057087 700__ $$aGili, M.
000057087 700__ $$aBotella, C.
000057087 700__ $$aBaños, R.
000057087 700__ $$aCastro, A.
000057087 700__ $$aRomero-Sanchiz, P.
000057087 700__ $$0(orcid)0000-0002-1690-4130$$aLópez-Del-Hoyo, Y.$$uUniversidad de Zaragoza
000057087 700__ $$aNogueira-Arjona, R.
000057087 700__ $$aVives, M.
000057087 700__ $$aRiera, A.
000057087 700__ $$0(orcid)0000-0002-3797-4218$$aGarcía-Campayo, J.$$uUniversidad de Zaragoza
000057087 7102_ $$14009$$2730$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicología Básica
000057087 7102_ $$11007$$2745$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Psiquiatría
000057087 773__ $$g18, 8 (2016), e231 [13 pp]$$pJMIR, J. med. internet res.$$tJOURNAL OF MEDICAL INTERNET RESEARCH$$x1438-8871
000057087 8564_ $$s839058$$uhttps://zaguan.unizar.es/record/57087/files/texto_completo.pdf$$yVersión publicada
000057087 8564_ $$s95904$$uhttps://zaguan.unizar.es/record/57087/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000057087 909CO $$ooai:zaguan.unizar.es:57087$$particulos$$pdriver
000057087 951__ $$a2020-02-21-13:30:42
000057087 980__ $$aARTICLE