Estimation of the relative sensitivity of qpcr analysis using pooled samples
Resumen: The high sensitivity of qPCR makes it a desirable diagnostic method in epidemiological surveillance programs. However, due to high costs, the use of pooling has been suggested. In this paper, an algorithm based on the Montecarlo method has been designed and implemented. The algorithm had been tested in many different situations, and finally it was validated with a real dataset. Moreover, based on the results obtained and depending on pooling conditions, a drastic decrease of sensitivity is observed.
Idioma: Inglés
DOI: 10.1371/journal.pone.0093491
Año: 2014
Publicado en: PLoS One 9, 4 (2014), e93491 [5 pp]
ISSN: 1932-6203

Factor impacto JCR: 3.234 (2014)
Categ. JCR: MULTIDISCIPLINARY SCIENCES rank: 9 / 57 = 0.158 (2014) - Q1 - T1
Factor impacto SCIMAGO:

Financiación: info:eu-repo/grantAgreement/ES/MICINN/MTM2010-21037
Tipo y forma: Article (Published version)
Área (Departamento): Matemática Aplicada (Departamento de Matemática Aplicada)
Área (Departamento): Sanidad Animal (Departamento de Patología Animal)

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Exportado de SIDERAL (2017-12-15-08:22:17)

Este artículo se encuentra en las siguientes colecciones:
Articles > Artículos por área > Matemática Aplicada
Articles > Artículos por área > Sanidad Animal

 Record created 2016-12-14, last modified 2017-12-15

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