000058348 001__ 58348
000058348 005__ 20190529115153.0
000058348 0247_ $$2doi$$a10.1039/c5nr01100k
000058348 0248_ $$2sideral$$a90365
000058348 037__ $$aART-2015-90365
000058348 041__ $$aeng
000058348 100__ $$0(orcid)0000-0001-5559-8757$$aFratila, R.M.$$uUniversidad de Zaragoza
000058348 245__ $$aShape matters: Synthesis and biomedical applications of high aspect ratio magnetic nanomaterials
000058348 260__ $$c2015
000058348 5060_ $$aAccess copy available to the general public$$fUnrestricted
000058348 5203_ $$aHigh aspect ratio magnetic nanomaterials possess anisotropic properties that make them attractive for biological applications. Their elongated shape enables multivalent interactions with receptors through the introduction of multiple targeting units on their surface, thus enhancing cell internalization. Moreover, due to their magnetic anisotropy, high aspect ratio nanomaterials can outperform their spherical analogues as contrast agents for magnetic resonance imaging (MRI) applications. In this review, we first describe the two main synthetic routes for the preparation of anisotropic magnetic nanomaterials: (i) direct synthesis (in which the anisotropic growth is directed by tuning the reaction conditions or by using templates) and (ii) assembly methods (in which the high aspect ratio is achieved by assembly from individual building blocks). We then provide an overview of the biomedical applications of anisotropic magnetic nanomaterials: magnetic separation and detection, targeted delivery and magnetic resonance imaging.
000058348 536__ $$9info:eu-repo/grantAgreement/EC/FP7/239931/EU/Multifunctional Magnetic Nanoparticles: Towards Smart Drugs Design/NANOPUZZLE
000058348 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000058348 590__ $$a7.76$$b2015
000058348 591__ $$aMATERIALS SCIENCE, MULTIDISCIPLINARY$$b23 / 271 = 0.085$$c2015$$dQ1$$eT1
000058348 591__ $$aNANOSCIENCE & NANOTECHNOLOGY$$b12 / 83 = 0.145$$c2015$$dQ1$$eT1
000058348 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b18 / 163 = 0.11$$c2015$$dQ1$$eT1
000058348 591__ $$aPHYSICS, APPLIED$$b12 / 145 = 0.083$$c2015$$dQ1$$eT1
000058348 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000058348 700__ $$0(orcid)0000-0003-0616-4383$$aRivera-Fernández, S.
000058348 700__ $$0(orcid)0000-0003-1081-8482$$ade la Fuente, J.M.$$uUniversidad de Zaragoza
000058348 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000058348 773__ $$g7, 18 (2015), 8233-8260$$pNanoscale$$tNANOSCALE$$x2040-3364
000058348 8564_ $$s6077765$$uhttp://zaguan.unizar.es/record/58348/files/texto_completo.pdf$$yPostprint
000058348 8564_ $$s93318$$uhttp://zaguan.unizar.es/record/58348/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000058348 909CO $$ooai:zaguan.unizar.es:58348$$particulos$$pdriver
000058348 951__ $$a2019-05-29-11:34:40
000058348 980__ $$aARTICLE