000062124 001__ 62124
000062124 005__ 20230830110634.0
000062124 0248_ $$2sideral$$a101416
000062124 0247_ $$2doi$$a10.20960/nh.257
000062124 037__ $$aART-2016-101416
000062124 041__ $$aeng
000062124 100__ $$0(orcid)0000-0002-7770-0203$$aSese, M.$$uUniversidad de Zaragoza
000062124 245__ $$aAssociation of body composition indices with insulin resistance in European adolescents: The HELENA study
000062124 260__ $$c2016
000062124 5060_ $$aAccess copy available to the general public$$fUnrestricted
000062124 5203_ $$aBackground: The different body components may contribute to the development of insulin resistance and type 2 diabetes mellitus. The aim of the present study was to examine the association of fat mass and fat free mass indices with markers of insulin resistance, independently of each other and giving, at the same time, gender-specific information in a wide cohort of European adolescents.
Methods: A cross-sectional study in a school setting was conducted in 925 (430 males) adolescents (14.9 ± 1.2 years). Weight, height, anthropometric, bioimpedance and blood parameters were measured. Indices for fat mass and fat free mass, and homeostatic model assessment (HOMA) were calculated. Multiple regression analyses were performed adjusting for several confounders including fat free mass and fat mass when possible.
Results: Indices of fat mass were positively associated with HOMA (all p < 0.01) after adjusting for all the confounders including fat free mass indices, in both sexes. Fat free mass indices were associated with HOMA, in both males and females, after adjusting for center, pubertal status, socioeconomic status and cardiorespiratory fitness, but the associations disappear when including fat mass indices in the adjustment’s model.
Conclusion: Fat mass indices derived from different methods are positively associated with insulin resistance independently of several confounders including fat free mass indices. In addition, the relationship of fat free mass with insulin resistance is influenced by the amount of fat mass in European adolescents. Nevertheless, future studies should focus not only on the role of fat mass, but also on other body components such as fat free mass because its role could vary depending of the level and distribution of fat mass.
000062124 536__ $$9info:eu-repo/grantAgreement/ES/Spanish Ministry of Health/RD08-0072$$9info:eu-repo/grantAgreement/ES/Spanish Ministry of Health/CIBERobn CB12-03-30038$$9info:eu-repo/grantAgreement/ES/MINECO/RYC-2014-16938$$9info:eu-repo/grantAgreement/EUR/FP6/FOOD-CT-2005-007034
000062124 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000062124 590__ $$a0.747$$b2016
000062124 591__ $$aNUTRITION & DIETETICS$$b68 / 80 = 0.85$$c2016$$dQ4$$eT3
000062124 592__ $$a0.4$$b2016
000062124 593__ $$aNutrition and Dietetics$$c2016$$dQ3
000062124 593__ $$aMedicine (miscellaneous)$$c2016$$dQ3
000062124 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000062124 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, L.A.$$uUniversidad de Zaragoza
000062124 700__ $$aCensi, L.
000062124 700__ $$aBresidenassel, C.
000062124 700__ $$aGonzález-Gross, M.
000062124 700__ $$aSjöström, M.
000062124 700__ $$aManios, Y.
000062124 700__ $$aDénes, M.
000062124 700__ $$aDallongeville, J.
000062124 700__ $$aWidhalm, K.
000062124 700__ $$aGottrand, F.
000062124 700__ $$aDe-Henauw, S.
000062124 700__ $$aMarcos, A.
000062124 700__ $$aCastillo-Garzón, M.
000062124 700__ $$aJiménez-Pavón, D.
000062124 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000062124 773__ $$g33, 3 (2016), 533-539$$pNutr. hosp.$$tNutricion Hospitalaria$$x0212-1611
000062124 85641 $$uhttp://revista.nutricionhospitalaria.net/index.php/nh/article/view/257/120$$zTexto completo de la revista
000062124 8564_ $$s735310$$uhttps://zaguan.unizar.es/record/62124/files/texto_completo.pdf$$yVersión publicada
000062124 8564_ $$s105248$$uhttps://zaguan.unizar.es/record/62124/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
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000062124 951__ $$a2023-08-30-10:57:01
000062124 980__ $$aARTICLE