| TAZ-TFG-2017-1370 |
La reacción de hipersensibilidad tipo I en la especie canina: dermatitis atópica canina y otras enfermedades alérgicas
Salord Torres, Francesc Xavier
Acín Tresaco, Cristina (dir.) ; Bolea Bailo, Rosa María (dir.)
Universidad de Zaragoza,
VET,
2017
Patología Animal department, Sanidad Animal area
Graduado en Veterinaria
Tipo de Trabajo Académico: Trabajo Fin de Grado
Notas: Type I Hypersensitivity reaction (immediate hypersensitivity) is an immediate reaction that occurs when antigen combines with preformed antibody (IgE) (created by a sensitizing exposure to the antigen) that is attached to mast cells triggering an instant reaction: inflammatory and vasoactive substances are released from mast cells granules, causing vasodilatation, oedema, eosinophil chemotaxis, pruritus and bronchoconstriction. Important . 4 TYPE I HIPERSENSITIVITY REACTION IN THE CANINE SPECIES Canine Atopic Dermatitis and other allergic diseases examples in veterinary Medicine of Immediate Hypersensitivity reactions include from systemic allergic disorders (anaphylaxis) to specific allergic disorders such as respiratory and ocular allergies (allergic rhinitis, bronchitis and conjunctivitis) and food and skin allergies. Skin allergic disorders are the most relevant in dogs, including a multifactorial syndrome suffered from 10 to 15% of dogs named Canine Atopic Dermatitis (CAD). In the first decade of the 20th century the Austrian scientist Clemens von Pirquet introduced the term 'allergy' into the world of human medicine. Later the concept was extended to the veterinary field and in 1941 clinical manifestations of canine atopy first were reported in a dog affected with seasonal allergic rhinitis. It is only in 1971 that the clinical signs of CAD initially were described. Allergic conditions usually are multifactorial involving both intrinsic factors, unique to the animal, and extrinsic factors, relating to both the environment and cutaneous microenvironment. A thorough understanding of these factors is needed if the condition wants to be managed successfully via current diagnostic and therapeutic tools.
Notas: Type I Hypersensitivity reaction (immediate hypersensitivity) is an immediate reaction that occurs when antigen combines with preformed antibody (IgE) (created by a sensitizing exposure to the antigen) that is attached to mast cells triggering an instant reaction: inflammatory and vasoactive substances are released from mast cells granules, causing vasodilatation, oedema, eosinophil chemotaxis, pruritus and bronchoconstriction. Important . 4 TYPE I HIPERSENSITIVITY REACTION IN THE CANINE SPECIES Canine Atopic Dermatitis and other allergic diseases examples in veterinary Medicine of Immediate Hypersensitivity reactions include from systemic allergic disorders (anaphylaxis) to specific allergic disorders such as respiratory and ocular allergies (allergic rhinitis, bronchitis and conjunctivitis) and food and skin allergies. Skin allergic disorders are the most relevant in dogs, including a multifactorial syndrome suffered from 10 to 15% of dogs named Canine Atopic Dermatitis (CAD). In the first decade of the 20th century the Austrian scientist Clemens von Pirquet introduced the term 'allergy' into the world of human medicine. Later the concept was extended to the veterinary field and in 1941 clinical manifestations of canine atopy first were reported in a dog affected with seasonal allergic rhinitis. It is only in 1971 that the clinical signs of CAD initially were described. Allergic conditions usually are multifactorial involving both intrinsic factors, unique to the animal, and extrinsic factors, relating to both the environment and cutaneous microenvironment. A thorough understanding of these factors is needed if the condition wants to be managed successfully via current diagnostic and therapeutic tools.
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trabajos-academicos-universidad-zaragoza > centro > facultad-de-veterinaria
trabajos-academicos-universidad-zaragoza > trabajos-fin-grado