000063115 001__ 63115
000063115 005__ 20181123104106.0
000063115 0248_ $$2sideral$$a98529
000063115 037__ $$aART-2016-98529
000063115 041__ $$aeng
000063115 100__ $$aLenis, Gustavo
000063115 245__ $$aPostextrasystolic T wave change to stratify risk of pump failure death in patients with chronic heart failure
000063115 260__ $$c2016
000063115 5060_ $$aAccess copy available to the general public$$fUnrestricted
000063115 5203_ $$aThe postextrasystolic T wave change (PEST) is an electrocardiographic phenomenon in which the morphology of the normal T wave is altered for a short time after a ventricular ectopic beat (VEB). It has been observed in patients with other cardiac pathologies but it has not been proposed as a risk index for cardiac death. Since PEST seems to be potentiated in patients with depression of myocardial contractility, we hypothesize that PEST could be used to predict pump failure death (PFD) in patients with chronic heart failure (CHF). For the purpose of quantifying PEST, the parameters morphological change onset (MCO) and morphological change slope (MCS) were introduced. MCO describes an initial morphological change of the T wave after a VEB, while MCS is responsible for the description of the restitution to its original shape. 537 records from the MUSIC study were separated according to their cause of death and comparisons against the others (including survivors) were carried out. In addition, receiver operating characteristic (ROC) curves were used to determine the optimal separating thresholds for MCO and MCS that maximized the sum of sensitivity and specificity for PFD risk prediction. The results showed that no significant differences could be established and the proposed parameters do not seem to be related to any kind of cardiac death. In future, other forms of PEST quantification together with more databases can be used to definitely conclude that PEST has no predictive power.
000063115 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000063115 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000063115 700__ $$aMenges, Robert.
000063115 700__ $$0(orcid)0000-0003-4130-5866$$aRamirez, Julia$$uUniversidad de Zaragoza
000063115 700__ $$aCygankiewicz, Iwona
000063115 700__ $$aBayés de Luna, Antoni
000063115 700__ $$0(orcid)0000-0002-7503-3339$$aMartinez, Juan Pablo$$uUniversidad de Zaragoza
000063115 700__ $$0(orcid)0000-0003-3434-9254$$aLaguna, Pablo$$uUniversidad de Zaragoza
000063115 700__ $$aDössel, Olaf
000063115 7102_ $$15008$$2800$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Teoría Señal y Comunicac.
000063115 773__ $$g43 (2016), 33-36$$pComput. cardiol.$$tComputing in Cardiology$$x2325-8861
000063115 85641 $$uhttp://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=7868672$$zTexto completo de la revista
000063115 8564_ $$s206782$$uhttps://zaguan.unizar.es/record/63115/files/texto_completo.pdf$$yVersión publicada
000063115 8564_ $$s109190$$uhttps://zaguan.unizar.es/record/63115/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000063115 909CO $$ooai:zaguan.unizar.es:63115$$particulos$$pdriver
000063115 951__ $$a2018-11-23-10:33:12
000063115 980__ $$aARTICLE