Sex bias in diagnostic delay in bronchiectasis: An analysis of the Spanish Historical Registry of Bronchiectasis
Girón, R.M. ; de Gracia Roldán, J. ; Olveira, C. ; Vendrell, M. ; Martínez-García, M.Á. ; de la Rosa, D. ; Máiz, L. ; Ancochea, J. ; Vázquez, L. ; Borderías, L. (Universidad de Zaragoza) ; Polverino, E. ; Martínez-Moragón, E. ; Rajas, O. ; Soriano, J.B.
Resumen: Diagnostic delay is common in most respiratory diseases, particularly in bronchiectasis. However, sex bias in diagnostic delay has not been studied to date. Objective: Assessment of diagnostic delay in bronchiectasis by sex. Methods: The Spanish Historical Registry of Bronchiectasis recruited adults diagnosed with bronchiectasis from 2002 to 2011 in 36 centres in Spain. From a total of 2113 patients registered we studied 2099, of whom 1125 (53.6%) were women. Results: No differences were found for sex or age (61.0 ± 20.6, p = 0.88) or for localization of bronchiectasis (p = 0.31). Bronchiectasis of unknown aetiology and secondary to asthma, childhood infections and tuberculosis was more common in women (all ps < 0.05). More men than women were chronic obstructive pulmonary disease-related bronchiectasis and colonized by Haemophilus influenzae (p < 0.001 for both). Onset of symptoms was earlier in women. The diagnostic delay for women with bronchiectasis was 2.1 years more than for men (p = 0.001). Discussion: We recorded a substantial delay in the diagnosis of bronchiectasis. This delay was significantly longer in women than in men (>2 years). Independent factors associated with this sex bias were age at onset of symptoms, smoking history, daily expectoration and reduced lung function.
Idioma: Inglés
DOI: 10.1177/1479972317702139
Año: 2017
Publicado en: Chronic respiratory disease 14, 4 (2017), 360-369
ISSN: 1479-9723
Factor impacto JCR: 2.275 (2017)
Categ. JCR: RESPIRATORY SYSTEM rank: 38 / 59 = 0.644 (2017) - Q3 - T2
Factor impacto SCIMAGO: 0.808 - Pulmonary and Respiratory Medicine (Q2)
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
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Idioma: Inglés
DOI: 10.1177/1479972317702139
Año: 2017
Publicado en: Chronic respiratory disease 14, 4 (2017), 360-369
ISSN: 1479-9723
Factor impacto JCR: 2.275 (2017)
Categ. JCR: RESPIRATORY SYSTEM rank: 38 / 59 = 0.644 (2017) - Q3 - T2
Factor impacto SCIMAGO: 0.808 - Pulmonary and Respiratory Medicine (Q2)
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2019-07-09-12:31:20)
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Record created 2018-01-12, last modified 2019-07-09