000069783 001__ 69783
000069783 005__ 20200609132533.0
000069783 0247_ $$2doi$$a10.1155/2018/4081874
000069783 0248_ $$2sideral$$a104943
000069783 037__ $$aART-2018-104943
000069783 041__ $$aeng
000069783 100__ $$aRuiz-del-Tiempo, M.P.
000069783 245__ $$aAnatomical Retinal Changes after Photodynamic Therapy in Chronic Central Serous Chorioretinopathy
000069783 260__ $$c2018
000069783 5060_ $$aAccess copy available to the general public$$fUnrestricted
000069783 5203_ $$aPurpose. To evaluate anatomical retinal changes measured by spectral-domain optical coherence tomography (SD-OCT), after applying photodynamic therapy (PDT) for treatment of chronic central serous chorioretinopathy (CSC).
Methods. A retrospective analysis was conducted on 43 patients (48 eyes) with chronic CSC treated with PDT. Visual acuity (VA), central retinal thickness (CRT), outer nuclear layer (ONL) thickness, subretinal fluid (SRF), and photoreceptor ellipsoid zone (EZ) measured by SD-OCT were collected at baseline and at 3, 6, and 12 months after PDT. Differences between normally distributed variables were calculated by a paired-sample t-test; p < 0 05 was considered statistically significant.
Results. Mean age was 50 +/- 9.8 years. Mean time from diagnosis to PDT was 12.5 months. Baseline VA was 0.51 +/- 0.24 and significantly improved (p < 0 001) to 0.74 +/- 0.26 one year after PDT. CRT and SRF significantly decreased (p < 0 001) at 3, 6, and 12 months after treatment. ONL thickness and EZ did not significantly change at any point during follow-up.
Conclusions. Not significant changes were found in the ONL or EZ 12 months after PDT.
000069783 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000069783 590__ $$a1.58$$b2018
000069783 591__ $$aOPHTHALMOLOGY$$b38 / 59 = 0.644$$c2018$$dQ3$$eT2
000069783 591__ $$aMEDICINE, RESEARCH & EXPERIMENTAL$$b104 / 135 = 0.77$$c2018$$dQ4$$eT3
000069783 592__ $$a0.818$$b2018
000069783 593__ $$aOphthalmology$$c2018$$dQ2
000069783 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000069783 700__ $$0(orcid)0000-0002-6202-2382$$aCalvo, P.$$uUniversidad de Zaragoza
000069783 700__ $$0(orcid)0000-0002-2914-2593$$aFerreras, A.$$uUniversidad de Zaragoza
000069783 700__ $$aLecinena, J.
000069783 700__ $$0(orcid)0000-0003-2389-8282$$aPablo, L.$$uUniversidad de Zaragoza
000069783 700__ $$0(orcid)0000-0001-6664-6275$$aRuiz-Moreno, O.$$uUniversidad de Zaragoza
000069783 7102_ $$11004$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía,Ginecol.Obstetr.$$cÁrea Oftalmología
000069783 773__ $$g2018, 4081874 (2018), [4 pp]$$pJ. Ophthalmol.$$tJournal of Ophthalmology$$x2090-004X
000069783 8564_ $$s2354280$$uhttps://zaguan.unizar.es/record/69783/files/texto_completo.pdf$$yVersión publicada
000069783 8564_ $$s26491$$uhttps://zaguan.unizar.es/record/69783/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000069783 909CO $$ooai:zaguan.unizar.es:69783$$particulos$$pdriver
000069783 951__ $$a2020-06-09-13:22:12
000069783 980__ $$aARTICLE