Anatomical Retinal Changes after Photodynamic Therapy in Chronic Central Serous Chorioretinopathy
Ruiz-del-Tiempo, M.P. ; Calvo, P. (Universidad de Zaragoza) ; Ferreras, A. (Universidad de Zaragoza) ; Lecinena, J. ; Pablo, L. (Universidad de Zaragoza) ; Ruiz-Moreno, O. (Universidad de Zaragoza)
Resumen: Purpose. To evaluate anatomical retinal changes measured by spectral-domain optical coherence tomography (SD-OCT), after applying photodynamic therapy (PDT) for treatment of chronic central serous chorioretinopathy (CSC).
Methods. A retrospective analysis was conducted on 43 patients (48 eyes) with chronic CSC treated with PDT. Visual acuity (VA), central retinal thickness (CRT), outer nuclear layer (ONL) thickness, subretinal fluid (SRF), and photoreceptor ellipsoid zone (EZ) measured by SD-OCT were collected at baseline and at 3, 6, and 12 months after PDT. Differences between normally distributed variables were calculated by a paired-sample t-test; p < 0 05 was considered statistically significant.
Results. Mean age was 50 +/- 9.8 years. Mean time from diagnosis to PDT was 12.5 months. Baseline VA was 0.51 +/- 0.24 and significantly improved (p < 0 001) to 0.74 +/- 0.26 one year after PDT. CRT and SRF significantly decreased (p < 0 001) at 3, 6, and 12 months after treatment. ONL thickness and EZ did not significantly change at any point during follow-up.
Conclusions. Not significant changes were found in the ONL or EZ 12 months after PDT.
Idioma: Inglés
DOI: 10.1155/2018/4081874
Año: 2018
Publicado en: Journal of Ophthalmology 2018, 4081874 (2018), [4 pp]
ISSN: 2090-004X
Factor impacto JCR: 1.58 (2018)
Categ. JCR: OPHTHALMOLOGY rank: 38 / 59 = 0.644 (2018) - Q3 - T2
Categ. JCR: MEDICINE, RESEARCH & EXPERIMENTAL rank: 104 / 135 = 0.77 (2018) - Q4 - T3
Factor impacto SCIMAGO: 0.818 - Ophthalmology (Q2)
Tipo y forma: Article (Published version)
Área (Departamento): Área Oftalmología (Dpto. Cirugía,Ginecol.Obstetr.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
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Methods. A retrospective analysis was conducted on 43 patients (48 eyes) with chronic CSC treated with PDT. Visual acuity (VA), central retinal thickness (CRT), outer nuclear layer (ONL) thickness, subretinal fluid (SRF), and photoreceptor ellipsoid zone (EZ) measured by SD-OCT were collected at baseline and at 3, 6, and 12 months after PDT. Differences between normally distributed variables were calculated by a paired-sample t-test; p < 0 05 was considered statistically significant.
Results. Mean age was 50 +/- 9.8 years. Mean time from diagnosis to PDT was 12.5 months. Baseline VA was 0.51 +/- 0.24 and significantly improved (p < 0 001) to 0.74 +/- 0.26 one year after PDT. CRT and SRF significantly decreased (p < 0 001) at 3, 6, and 12 months after treatment. ONL thickness and EZ did not significantly change at any point during follow-up.
Conclusions. Not significant changes were found in the ONL or EZ 12 months after PDT.
Idioma: Inglés
DOI: 10.1155/2018/4081874
Año: 2018
Publicado en: Journal of Ophthalmology 2018, 4081874 (2018), [4 pp]
ISSN: 2090-004X
Factor impacto JCR: 1.58 (2018)
Categ. JCR: OPHTHALMOLOGY rank: 38 / 59 = 0.644 (2018) - Q3 - T2
Categ. JCR: MEDICINE, RESEARCH & EXPERIMENTAL rank: 104 / 135 = 0.77 (2018) - Q4 - T3
Factor impacto SCIMAGO: 0.818 - Ophthalmology (Q2)
Tipo y forma: Article (Published version)
Área (Departamento): Área Oftalmología (Dpto. Cirugía,Ginecol.Obstetr.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. Exportado de SIDERAL (2020-06-09-13:22:12)
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Record created 2018-04-13, last modified 2020-06-09