000069987 001__ 69987
000069987 005__ 20220322103046.0
000069987 0247_ $$2doi$$a10.1186/s12888-018-1638-6
000069987 0248_ $$2sideral$$a105438
000069987 037__ $$aART-2018-105438
000069987 041__ $$aeng
000069987 100__ $$aVara, M.D.
000069987 245__ $$aEfficacy and cost-effectiveness of a blended cognitive behavioral therapy for depression in Spanish primary health care: Study protocol for a randomised non-inferiority trial
000069987 260__ $$c2018
000069987 5060_ $$aAccess copy available to the general public$$fUnrestricted
000069987 5203_ $$aBackground: Data from primary health care in Spain show a high prevalence of the major depressive disorder. Blended treatment (combination of face-to-face and online components) seems to be a very promising tool for the optimization and dissemination of psychological treatments in a cost-effective form. Although there is growing data that confirm the advantages of blended therapies, few studies have analyzed their application in regular clinical practice. The objective of the present paper is to describe the protocol for a clinical study aimed at exploring the clinical and cost-effectiveness of a blended cognitive behavioral therapy (b-CBT) for depression, compared to treatment as usual (TAU) in a primary health care setting. Methods: A two-arm randomised controlled non-inferiority trial will be carried out, with repeated measures (baseline, 3 months, 6 months, and 12 months) under two conditions: b-CBT and TAU. The b-CBT program will consist in three face-to-face sessions and eight online sessions. The TAU is defined as the routine care delivered by the general practitioner for the treatment of depression in primary care. The primary outcome is a symptomatic change of depressive symptoms on the patient-health questionnaire (PHQ-9). Other secondary outcomes will be considered (e.g., quality of life, treatment preference). All participants must be 18 years of age or older and meet the diagnostic criteria for major depressive disorder according to the Diagnostic and Statistical Manual of Mental disorders 4th edition. 156 participants will be recruited (78 per arm). Discussion: It is expected that b-CBT is clinically non-inferior when compared to TAU. This is the first study in Spain to use a b-CBT format in primary and specialized care, and this format could be an efficacious and cost-effective therapeutic strategy for the treatment of depression.
000069987 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/PSI2014-56303-REDT$$9info:eu-repo/grantAgreement/ES/ISCIII/CB06-03-0052$$9info:eu-repo/grantAgreement/EC/FP7/603098/EU/European-COMPARative Effectiveness research on online Depression/E-COMPARED
000069987 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000069987 590__ $$a2.666$$b2018
000069987 591__ $$aPSYCHIATRY$$b67 / 146 = 0.459$$c2018$$dQ2$$eT2
000069987 592__ $$a1.306$$b2018
000069987 593__ $$aPsychiatry and Mental Health$$c2018$$dQ1
000069987 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000069987 700__ $$0(orcid)0000-0001-6987-6607$$aHerrero, R.
000069987 700__ $$0(orcid)0000-0002-6266-9602$$aEtchemendy, E.$$uUniversidad de Zaragoza
000069987 700__ $$aEspinoza, M.
000069987 700__ $$aBaños, R.M.
000069987 700__ $$aGarcía-Palacios, A.
000069987 700__ $$aLera, G.
000069987 700__ $$aFolch, B.
000069987 700__ $$aPalop-Larrea, V.
000069987 700__ $$aVázquez, P.
000069987 700__ $$aFranco-Martín, M.
000069987 700__ $$aKleiboer, A.
000069987 700__ $$aRiper, H.
000069987 700__ $$aBotella, C.
000069987 7102_ $$14009$$2680$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Person.Eval.Trat.Psicoló.
000069987 773__ $$g18, 1 (2018), 74 [9 pp.]$$pBMC Psychiatry$$tBMC Psychiatry$$x1471-244X
000069987 8564_ $$s594766$$uhttps://zaguan.unizar.es/record/69987/files/texto_completo.pdf$$yVersión publicada
000069987 8564_ $$s87332$$uhttps://zaguan.unizar.es/record/69987/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
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000069987 951__ $$a2022-03-22-10:15:56
000069987 980__ $$aARTICLE