000070219 001__ 70219
000070219 005__ 20240122154813.0
000070219 0247_ $$2doi$$a10.1186/s12886-018-0728-z
000070219 0248_ $$2sideral$$a105475
000070219 037__ $$aART-2018-105475
000070219 041__ $$aeng
000070219 100__ $$aCasas, P.
000070219 245__ $$aVisual field defects and retinal nerve fiber imaging in patients with obstructive sleep apnea syndrome and in healthy controls
000070219 260__ $$c2018
000070219 5060_ $$aAccess copy available to the general public$$fUnrestricted
000070219 5203_ $$aBackground: To assess the retinal sensitivity in obstructive sleep apnea hypopnea syndrome (OSAHS) patients evaluated with standard automated perimetry (SAP). And to correlate the functional SAP results with structural parameters obtained with optical coherence tomography (OCT). Methods: This prospective, observational, case-control study consisted of 63 eyes of 63 OSAHS patients (mean age 51.7 ± 12.7 years, best corrected visual acuity =20/25, refractive error less than three spherical or two cylindrical diopters, and intraocular pressure < 21 mmHg) who were enrolled and compared with 38 eyes of 38 age-matched controls. Peripapillary retinal nerve fiber layer (RNFL) thickness was measured by Stratus OCT and SAP sensitivities and indices were explored with Humphrey Field Analyzer perimeter. Correlations between functional and structural parameters were calculated, as well as the relationship between ophthalmologic and systemic indices in OSAHS patients. Results: OSAHS patients showed a significant reduction of the sensitivity for superior visual field division (p = 0.034, t-student test). When dividing the OSAHS group in accordance with the severity of the disease, nasal peripapillary RNFL thickness was significantly lower in severe OSAHS than that in controls and mild-moderate cases (p = 0.031 and p = 0.016 respectively, Mann-Whitney U test). There were no differences between groups for SAP parameters. We found no correlation between structural and functional variables. The central visual field sensitivity of the SAP revealed a poor Pearson correlation with the apnea-hipopnea index (0.284, p = 0.024). Conclusions: Retinal sensitivity show minor differences between healthy subjects and OSAHS. Functional deterioration in OSAHS patients is not easy to demonstrate with visual field examination.
000070219 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000070219 590__ $$a1.431$$b2018
000070219 591__ $$aOPHTHALMOLOGY$$b44 / 59 = 0.746$$c2018$$dQ3$$eT3
000070219 592__ $$a0.833$$b2018
000070219 593__ $$aOphthalmology$$c2018$$dQ2
000070219 593__ $$aMedicine (miscellaneous)$$c2018$$dQ2
000070219 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000070219 700__ $$0(orcid)0000-0001-9876-5850$$aAscaso, F.J.$$uUniversidad de Zaragoza
000070219 700__ $$0(orcid)0000-0001-6724-5158$$aVicente, E.$$uUniversidad de Zaragoza
000070219 700__ $$aTejero-Garcés, G.
000070219 700__ $$0(orcid)0000-0002-3265-504X$$aAdiego, M.I.$$uUniversidad de Zaragoza
000070219 700__ $$aCristóbal, J.A.
000070219 7102_ $$11004$$2653$$aUniversidad de Zaragoza$$bDpto. Cirugía,Ginecol.Obstetr.$$cÁrea Otorrinolaringología
000070219 7102_ $$11004$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía,Ginecol.Obstetr.$$cÁrea Oftalmología
000070219 773__ $$g18, 1 (2018), 66 [9 pp]$$pBMC OPHTHALMOLOGY$$tBMC OPHTHALMOLOGY$$x1471-2415
000070219 8564_ $$s587626$$uhttps://zaguan.unizar.es/record/70219/files/texto_completo.pdf$$yVersión publicada
000070219 8564_ $$s99192$$uhttps://zaguan.unizar.es/record/70219/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000070219 909CO $$ooai:zaguan.unizar.es:70219$$particulos$$pdriver
000070219 951__ $$a2024-01-22-15:32:21
000070219 980__ $$aARTICLE