@article{Silva:8415,
      author        = "Silva, Manuel Agustín and Abecia Martínez, Alfonso",
      title         = "{Uso de la combinación de melatonina y prostaglandinas
                       para la sincronización del estro en ovejas de raza rasa
                       aragonesa}",
      year          = "2012",
      note          = "The goal of this work was to use exogenous melatonin in
                       combination with PGF2α on spring, to study its efficacy in
                       the oestrus sinchronization in sheep. Fifty-one female and
                       4 male Rasa Aragonesa sheep were included in the study.
                       Ewes were divided in three experimental groups based on the
                       treatment received. One group was treated with melatonin,
                       another was treated with melatonin along with a single shot
                       of PGF2α and the last one was the control group. Rams and
                       ewes were kept apart until the end of their treatment and
                       were put together for the breeding. Blood samples from the
                       female were taken and processed to establish the
                       concentration of progesterone, in order to know their
                       reproductive status; these samples were collected seven
                       days prior to the introduction of males, the day of the
                       introduction and seven days after the introduction.
                       Progesterone concentrations showed that 100% of the female
                       sheep had a cyclical activity before the introduction of
                       the male sheep. Ewes were in oestrus from the day of
                       introduction of the male into the pen, and the group
                       treated with PGF2α showed oestrous sinchronization the
                       first days of breeding. On day 2, 41% of the individuals
                       were in heat. The other two groups, the one treated with
                       melatonin and the control group, showed a fast and growing
                       sexual activity, which can be attributed to the fact that
                       the female were already in cyclic stage and to a likely
                       effect of “sympathy”. Regarding the pregnancy rate, it
                       is worth noting that it was low (55%) and with no
                       significant differences among the groups (59% for the group
                       treated with prostaglandine and 53% in the other two). This
                       was possibly due to the high number of sheep in heat in a
                       short period of time which prevented the male sheep to mate
                       all of them and the stress the animals were subjected
                       throughout the whole experience. In conclusion, the
                       combination of melatonin implants and a single shot of
                       PGF2α in spring showed the capability of sinchronizing the
                       oestrus in the group treated, although without reaching the
                       usual figures of the traditional treated with PGF2α and
                       double shots within 7-10 days.",
}