Resumen: The patient is a 57-year-old man with liver cirrhosis, Bricker anastomosis after a radical cystoprostatectomy and, a history of bacteremias caused by extended-spectrum -lactamase-positive Escherichia coli, Enterococcus faecium, and Candida albicans. He presented with persistent low back pain and was diagnosed with vertebral osteomyelitis, for which he received ertapenem-linezolid treatment. However, after 20 days, linezolid had to be discontinued because of myelotoxicity and metabolic acidosis. The patient was switched to tedizolid, which, in combination with ertapenem, was successfully given for 114 days until biopsy showed no growth of gram-positive cocci. We conclude that tedizolid can be an alternative to linezolid in case of toxicity, especially in long-term treatments. Idioma: Inglés DOI: 10.1097/IPC.0000000000000623 Año: 2018 Publicado en: INFECTIOUS DISEASES IN CLINICAL PRACTICE 26, 6 (2018), E67-E69 ISSN: 1056-9103 Factor impacto SCIMAGO: 0.171 - Microbiology (medical) (Q4) - Infectious Diseases (Q4)