000086253 001__ 86253 000086253 005__ 20231219145818.0 000086253 0247_ $$2doi$$a10.1186/s12888-019-2298-x 000086253 0248_ $$2sideral$$a114831 000086253 037__ $$aART-2019-114831 000086253 041__ $$aeng 000086253 100__ $$aLopez-Montoyo, Alba 000086253 245__ $$aEffectiveness of a brief psychological mindfulness-based intervention for the treatment of depression in primary care: Study protocol for a randomized controlled clinical trial 000086253 260__ $$c2019 000086253 5060_ $$aAccess copy available to the general public$$fUnrestricted 000086253 5203_ $$aBackground: Depressive symptoms are quite prevalent in Primary Care (PC) settings. The treatment as usual (TAU) in PC is pharmacotherapy, despite the high relapse rates it produces. Many patients would prefer psychotherapy, but specialized services are overloaded. Studies that apply Mindfulness-Based Interventions (MBIs) for the treatment of depression have obtained significant improvements. Brief low-intensity approaches delivered from PC could be a promising approach. This study aims to compare a low-intensity mindfulness intervention for the treatment of depression in PC using different intervention formats - a face-to-face MBI delivered in a group and the same MBI individually applied on the Internet - to a control group that will receive PC medical treatment as usual. Methods: A randomized controlled clinical trial will be conducted in PC, with about 120 depressed patients allocated (1:1:1) to three groups: "face-to-face MBI + TAU", "Internet-delivered MBI + TAU", and "TAU alone". The MBI programs will be composed of four modules. The primary outcome will be depressive symptoms, measured through the Beck Depression Inventory, assessed at pre- and post-treatment and 6- and 12-month follow-ups. Other outcomes will be mindfulness, happiness, affectivity, quality of life, and the use of healthcare services. Intention-to-treat analysis using linear mixed models adjusted for baseline scores and routine sociodemographic analysis that could show baseline differences will be conducted. Per-protocol secondary outcome analyses will also be performed. Discussion: This is the first Spanish RCT to apply a low-intensity face-to-face MBI (plus TAU) to treat depression in PC settings compared to TAU (alone). Moreover, this study will also make it possible to evaluate the same MBI program (plus TAU), but Internet-delivered, considering their cost-effectiveness. Positive results from this RCT might have an important impact on mental health settings, helping to decrease the overload of the system and offering treatment alternatives beyond antidepressant medication through high-quality, flexible PC interventions. 000086253 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII-MINECO/PI16-00962$$9info:eu-repo/grantAgreement/ES/ISCIII/RD16-0007-0005 000086253 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000086253 590__ $$a2.704$$b2019 000086253 591__ $$aPSYCHIATRY$$b68 / 154 = 0.442$$c2019$$dQ2$$eT2 000086253 592__ $$a1.341$$b2019 000086253 593__ $$aPsychiatry and Mental Health$$c2019$$dQ1 000086253 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000086253 700__ $$aQuero, Soledad 000086253 700__ $$0(orcid)0000-0001-5677-1662$$aMontero-Marín, Jesús 000086253 700__ $$0(orcid)0000-0002-2116-9257$$aBarcelo-Soler, Alberto 000086253 700__ $$0(orcid)0000-0003-0786-535X$$aBeltrán, María 000086253 700__ $$0(orcid)0000-0001-9903-4064$$aCampos, Daniel 000086253 700__ $$0(orcid)0000-0002-3797-4218$$aGarcía-Campayo, Javier$$uUniversidad de Zaragoza 000086253 7102_ $$11007$$2745$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Psiquiatría 000086253 773__ $$g19, 301 (2019), s12888-019-2298-x [12 pp.]$$pBMC Psychiatry$$tBMC Psychiatry$$x1471-244X 000086253 8564_ $$s692280$$uhttps://zaguan.unizar.es/record/86253/files/texto_completo.pdf$$yVersión publicada 000086253 8564_ $$s93246$$uhttps://zaguan.unizar.es/record/86253/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000086253 909CO $$ooai:zaguan.unizar.es:86253$$particulos$$pdriver 000086253 951__ $$a2023-12-19-14:44:31 000086253 980__ $$aARTICLE