Resumen: The Fournier’s Gangrene is a necrotizing infection which is located in the perineal area. It ́s a severe infection, which involves a quick evolution to advanced stages where a high morbimortality rate is associated. However, it often tends to be underdiagnosed in early stages. The most important in the diagnosis is a high clinical suspicion and subsequent surgical treatment which is base on a desbridalment and exeresis of the affected tissues. In addition, the association of broad-spectrum antibiotic therapy and nutritional support are crucial. This report reviews a clinical case of Fournier's Gangrene, in a patient with a history of radiation induced cystitis and pubic osteitis after pelvic radiotherapy, diagnosed and treated with a radical hemivulvectomy, antibiotic therapy and lavages in our Hospital. Idioma: Español DOI: 10.4067/S0717-75262019000300225 Año: 2019 Publicado en: Revista Chilena de Obstetricia y Ginecologia 84, 3 (2019), 225-230 ISSN: 0048-766X Factor impacto SCIMAGO: 0.132 - Obstetrics and Gynecology (Q4)