000089953 001__ 89953
000089953 005__ 20200630162510.0
000089953 0247_ $$2doi$$a10.1111/tmi.12703
000089953 0248_ $$2sideral$$a118046
000089953 037__ $$aART-2016-118046
000089953 041__ $$aeng
000089953 100__ $$0(orcid)0000-0001-6756-9515$$aMartínez Pérez, Guillermo
000089953 245__ $$aSupervised oral HIV self-testing is accurate in rural KwaZulu Natal, South Africa
000089953 260__ $$c2016
000089953 5060_ $$aAccess copy available to the general public$$fUnrestricted
000089953 5203_ $$aObjectives: To achieve UNAIDS 90-90-90 targets, alternatives to conventional HIV testing models are necessary in South Africa to increase population awareness of their HIV status. One of the alternatives is oral mucosal transudates-based HIV self-testing (OralST). This study describes implementation of counsellor-introduced supervised OralST in a high HIV prevalent rural area. Methods: Cross-sectional study conducted in two government-run primary healthcare clinics and three Médecins Sans Frontières-run fixed-testing sites in uMlalazi municipality, KwaZulu-Natal. Lay counsellors sampled and recruited eligible participants, sought informed consent and demonstrated the use of the OraQuick(™) OralST. The participants used the OraQuick(™) in front of the counsellor and underwent a blood-based Determine(™) and a Unigold(™) rapid diagnostic test as gold standard for comparison. Primary outcomes were user error rates, inter-rater agreement, sensitivity, specificity and predictive values. Results: A total of 2198 participants used the OraQuick(™) , of which 1005 were recruited at the primary healthcare clinics. Of the total, 1457 (66.3%) were women. Only two participants had to repeat their OraQuick(™) . Inter-rater agreement was 99.8% (Kappa 0.9925). Sensitivity for the OralST was 98.7% (95% CI 96.8-99.6), and specificity was 100% (95% CI 99.8-100). Conclusion: This study demonstrates high inter-rater agreement, and high accuracy of supervised OralST. OralST has the potential to increase uptake of HIV testing and could be offered at clinics and community testing sites in rural South Africa. Further research is necessary on the potential of unsupervised OralST to increase HIV status awareness and linkage to care.
000089953 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000089953 590__ $$a2.85$$b2016
000089953 591__ $$aTROPICAL MEDICINE$$b2 / 19 = 0.105$$c2016$$dQ1$$eT1
000089953 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b39 / 176 = 0.222$$c2016$$dQ1$$eT1
000089953 592__ $$a1.583$$b2016
000089953 593__ $$aInfectious Diseases$$c2016$$dQ1
000089953 593__ $$aPublic Health, Environmental and Occupational Health$$c2016$$dQ1
000089953 593__ $$aParasitology$$c2016$$dQ1
000089953 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000089953 700__ $$aSteele, Sarah J.
000089953 700__ $$aGovender, Indira
000089953 700__ $$aArellano, Gemma
000089953 700__ $$aMkwamba, Alec
000089953 700__ $$aHadebe, Menzi
000089953 700__ $$aCutsem, Gilles van
000089953 773__ $$g21, 6 (2016), 759-767$$pTM IH, Trop. med. int. health$$tTROPICAL MEDICINE & INTERNATIONAL HEALTH$$x1360-2276
000089953 8564_ $$s146779$$uhttps://zaguan.unizar.es/record/89953/files/texto_completo.pdf$$yVersión publicada
000089953 8564_ $$s22777$$uhttps://zaguan.unizar.es/record/89953/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000089953 909CO $$ooai:zaguan.unizar.es:89953$$particulos$$pdriver
000089953 951__ $$a2020-06-30-14:28:02
000089953 980__ $$aARTICLE