@article{CórdovaSalas:9008,
      author        = "Córdova Salas, Ana Karina and Garagorri Otero, Jesús
                       María and Labarta Aizpún, José Ignacio",
      title         = "{Efectos de los corticoides inhalados sobre la densidad
                       mineral ósea en niños con asma bronquial}",
      year          = "2012",
      note          = "Today, it is known that the systemic effects of inhaled
                       glucocorticoids, such as suppression of the
                       hypothalamic-pituitary-adrenal axis are less pronounced
                       than with oral corticosteroids, however, there are still
                       few studies on the adverse effects of treatment
                       administration as chronic. The objectives of the study were
                       to assess whether there is involvement in bone mineral
                       density, height, weight, in children with continuous
                       treatment with inhaled corticosteroids and whether there
                       are differences between steroid use and the diagnostic
                       methods used. The study was descriptive-analytical
                       cross-sectional. Children 2-15 years with a diagnosis of
                       bronchial asthma with prolonged treatment with inhaled
                       corticosteroids who attended at Miguel Servet’s Hospital
                       between November 2011 and June 2012 participated. The
                       records noting: starting day of inhaled corticosteroids,
                       type of steroid, dose previously received, height, age,
                       weight, BMI, pubertal stage. Later all of them were bone
                       density measurement using ultrasound (US) methods and
                       subsequently DXA lumbar by family consent. There was no
                       involvement of bone mineral density and changes in terms of
                       height and weight in children with continuous treatment
                       with inhaled corticosteroids. No significant difference was
                       found between budesonide versus fluticasone regarding
                       alteration of bone mineral density. We found a weak
                       positive correlation between the values of Z-score of
                       ultrasound versus DXA. In conclusion, the prolonged use of
                       mild to moderate doses of inhaled corticosteroids in asthma
                       patients no influence on the decrease in children’s bone
                       mass.",
}