@article{CórdovaSalas:9008,
author = "Córdova Salas, Ana Karina and Garagorri Otero, Jesús
María and Labarta Aizpún, José Ignacio",
title = "{Efectos de los corticoides inhalados sobre la densidad
mineral ósea en niños con asma bronquial}",
year = "2012",
note = "Today, it is known that the systemic effects of inhaled
glucocorticoids, such as suppression of the
hypothalamic-pituitary-adrenal axis are less pronounced
than with oral corticosteroids, however, there are still
few studies on the adverse effects of treatment
administration as chronic. The objectives of the study were
to assess whether there is involvement in bone mineral
density, height, weight, in children with continuous
treatment with inhaled corticosteroids and whether there
are differences between steroid use and the diagnostic
methods used. The study was descriptive-analytical
cross-sectional. Children 2-15 years with a diagnosis of
bronchial asthma with prolonged treatment with inhaled
corticosteroids who attended at Miguel Servet’s Hospital
between November 2011 and June 2012 participated. The
records noting: starting day of inhaled corticosteroids,
type of steroid, dose previously received, height, age,
weight, BMI, pubertal stage. Later all of them were bone
density measurement using ultrasound (US) methods and
subsequently DXA lumbar by family consent. There was no
involvement of bone mineral density and changes in terms of
height and weight in children with continuous treatment
with inhaled corticosteroids. No significant difference was
found between budesonide versus fluticasone regarding
alteration of bone mineral density. We found a weak
positive correlation between the values of Z-score of
ultrasound versus DXA. In conclusion, the prolonged use of
mild to moderate doses of inhaled corticosteroids in asthma
patients no influence on the decrease in children’s bone
mass.",
}