000095076 001__ 95076
000095076 005__ 20210902121743.0
000095076 0247_ $$2doi$$a10.3390/jcm9051563
000095076 0248_ $$2sideral$$a118737
000095076 037__ $$aART-2020-118737
000095076 041__ $$aeng
000095076 100__ $$aClerencia-Sierra, M.
000095076 245__ $$aDo centenarians die healthier than younger elders? A comparative epidemiological study in Spain
000095076 260__ $$c2020
000095076 5060_ $$aAccess copy available to the general public$$fUnrestricted
000095076 5203_ $$aThis study aims to describe the clinical course, drug use, and health services use characteristics during the last year of life of elders who die being centenarians and to identify key aspects differentiating them from elders who die at an earlier age, with a particular focus on sex differences. We conducted an observational, population-based study in the EpiChron Cohort (Aragon, Spain). The population was stratified by sex and into three age sub-populations (80-89, 90-99, and >= 100 years), and their characteristics were described and compared. Multimorbidity was the rule in our elders, affecting up to 3 in 4 centenarians and 9 in 10 octogenarians and nonagenarians. Polypharmacy was also observed in half of the centenarian population and in most of the younger elders. Risk factors for cardiovascular disease (i.e., hypertension, dyslipidaemia, diabetes), cerebrovascular disease and dementia were amongst the most common chronic conditions in all age groups, whereas the gastroprotective drugs and antithrombotic agents were the most dispensed drugs. Centenarians presented in general lower morbidity and treatment burden and lower use of both primary and hospital healthcare services than octogenarians and nonagenarians, suggesting a better health status. Sex-differences in their clinical characteristics were more striking in octogenarians and tended to decrease with age.
000095076 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/B01-20R
000095076 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000095076 590__ $$a4.241$$b2020
000095076 591__ $$aMEDICINE, GENERAL & INTERNAL$$b39 / 169 = 0.231$$c2020$$dQ1$$eT1
000095076 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000095076 700__ $$aIoakeim-Skoufa, I.
000095076 700__ $$aPoblador-Plou, B.
000095076 700__ $$aGonzalez-Rubio, F.
000095076 700__ $$aAza-Pascual-Salcedo, M.
000095076 700__ $$aMachon, M.
000095076 700__ $$0(orcid)0000-0002-5440-1710$$aGimeno-Miguel, A.
000095076 700__ $$aPrados-Torres, A.
000095076 773__ $$g9, 5 (2020), 1563 [11 pp.]$$pJ. clin.med.$$tJOURNAL OF CLINICAL MEDICINE$$x2077-0383
000095076 8564_ $$s261636$$uhttps://zaguan.unizar.es/record/95076/files/texto_completo.pdf$$yVersión publicada
000095076 8564_ $$s480295$$uhttps://zaguan.unizar.es/record/95076/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000095076 909CO $$ooai:zaguan.unizar.es:95076$$particulos$$pdriver
000095076 951__ $$a2021-09-02-09:43:31
000095076 980__ $$aARTICLE