Effect of a multi-citrus extract-based feed additive on the survival of rainbow trout (Oncorhynchus mykiss) following challenge with Lactococcus garvieae

Mora-Sánchez, B. ; Fuertes, H. ; Balcázar, J.L. ; Pérez-Sánchez, T. (Universidad de Zaragoza)

Resumen: Growing global concerns about antibiotic resistance have generated a considerable interest in the search for alternative environmental-friendly approaches. This study was aimed to assess the antimicrobial activity of a multi-citrus extract-based feed additive (Biocitro®) against some fish pathogens, as well as evaluate its capacity to protect rainbow trout (Oncorhynchus mykiss) to lactococcosis. A broth dilution method was used to determine the minimum inhibitory concentration (MIC) of Biocitro®, and the results showed a strong antibacterial activity against Aeromonas salmonicida, Lactococcus garvieae and Yersinia ruckeri with MIC values of 2.0 µg/mL. Afterwards, rainbow trout juveniles were fed a Biocitro®-enriched diet (750 mg/kg feed) at a daily rate of 1.5% body weight for 4 weeks, then they were challenged with L. garvieae by the cohabitation method. At the end of the experimental period, fish treated with Biocitro® showed significantly (P¿<¿0.001) improved protection against L. garvieae compared to control fish. Although further studies are needed to understand how Biocitro® increases rainbow trout resistance to L. garvieae, this feed additive could be considered as a useful alternative to chemotherapeutic treatment in aquaculture.

Idioma: Inglés

DOI: 10.1186/s13028-020-00536-0

Año: 2020

Publicado en: Acta veterinaria Scandinavica 62, 1 (2020), 38 [4 pp.]
ISSN: 0044-605X

Factor impacto JCR: 1.695 (2020)

Categ. JCR: VETERINARY SCIENCES rank: 58 / 146 = 0.397 (2020) - Q2 - T2

Factor impacto SCIMAGO: 0.607 - Veterinary (miscellaneous) (Q1) - Medicine (miscellaneous) (Q1)

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Sanidad Animal (Dpto. Patología Animal)