000100754 001__ 100754
000100754 005__ 20210318131602.0
000100754 0247_ $$2doi$$a10.1097/QAD.0000000000002294
000100754 0248_ $$2sideral$$a123615
000100754 037__ $$aART-2019-123615
000100754 041__ $$aeng
000100754 100__ $$aCrichton, S.
000100754 245__ $$aHeight and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand
000100754 260__ $$c2019
000100754 5060_ $$aAccess copy available to the general public$$fUnrestricted
000100754 5203_ $$aObjective: The aim of this study was to describe growth during puberty in young people with vertically acquired HIV.
Design: Pooled data from 12 paediatric HIV cohorts in Europe and Thailand.
Methods: One thousand and ninety-four children initiating a nonnucleoside reverse transcriptase inhibitor or boosted protease inhibitor based regimen aged 1-10 years were included. Super Imposition by Translation And Rotation (SITAR) models described growth from age 8 years using three parameters (average height, timing and shape of the growth spurt), dependent on age and height-for-age z-score (HAZ) (WHO references) at antiretroviral therapy (ART) initiation. Multivariate regression explored characteristics associated with these three parameters.
Results: At ART initiation, median age and HAZ was 6.4 [interquartile range (IQR): 2.8, 9.0] years and -1.2 (IQR: -2.3 to -0.2), respectively. Median follow-up was 9.1 (IQR: 6.9, 11.4) years. In girls, older age and lower HAZ at ART initiation were independently associated with a growth spurt which occurred 0.41 (95% confidence interval 0.20-0.62) years later in children starting ART age 6 to 10 years compared with 1 to 2 years and 1.50 (1.21-1.78) years later in those starting with HAZ less than -3 compared with HAZ at least -1. Later growth spurts in girls resulted in continued height growth into later adolescence. In boys starting ART with HAZ less than -1, growth spurts were later in children starting ART in the oldest age group, but for HAZ at least -1, there was no association with age. Girls and boys who initiated ART with HAZ at least -1 maintained a similar height to the WHO reference mean.
Conclusion: Stunting at ART initiation was associated with later growth spurts in girls. Children with HAZ at least -1 at ART initiation grew in height at the level expected in HIV negative children of a comparable age.
000100754 536__ $$9info:eu-repo/grantAgreement/ES/FECYT/FIPSE-240800-09$$9info:eu-repo/grantAgreement/ES/FECYT/FIPSE-3608229-09$$9info:eu-repo/grantAgreement/ES/FECYT/FIPSE-361910-10$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER-CoRISpe-RED RIS/RD06-0006-0021$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER-CoRISpe-RED RIS/RD06-0006-0035$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER-FIS/PI15-00694$$9info:eu-repo/grantAgreement/ES/ISCIII/RD12-0017-0035$$9info:eu-repo/grantAgreement/ES/ISCIII/RD12-0017-0037
000100754 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000100754 590__ $$a4.511$$b2019
000100754 591__ $$aINFECTIOUS DISEASES$$b19 / 93 = 0.204$$c2019$$dQ1$$eT1
000100754 591__ $$aVIROLOGY$$b7 / 37 = 0.189$$c2019$$dQ1$$eT1
000100754 591__ $$aIMMUNOLOGY$$b49 / 158 = 0.31$$c2019$$dQ2$$eT1
000100754 592__ $$a2.447$$b2019
000100754 593__ $$aImmunology$$c2019$$dQ1
000100754 593__ $$aInfectious Diseases$$c2019$$dQ1
000100754 593__ $$aImmunology and Allergy$$c2019$$dQ1
000100754 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000100754 700__ $$aBelfrage, E.
000100754 700__ $$aCollins, I.J.
000100754 700__ $$aDoerholt, K.
000100754 700__ $$aJudd, A.
000100754 700__ $$aLe Coeur, S.
000100754 700__ $$aSpoulou, V.
000100754 700__ $$aGoodall, R.
000100754 700__ $$aScherpbier, H.
000100754 700__ $$aSmit, C.
000100754 700__ $$aGoetghebuer, T.
000100754 700__ $$aGibb, D.M.
000100754 700__ $$aNoguera, A.
000100754 700__ $$aNavarro, M.L.
000100754 700__ $$aRamos, J.T.
000100754 700__ $$aGalli, L.
000100754 700__ $$aGiaquinto, C.
000100754 700__ $$aThorne, C.
000100754 700__ $$aSanta Ansone.
000100754 700__ $$aMarczynska, M.
000100754 700__ $$aOkhonskaia, L.
000100754 700__ $$ade Tejada, BM.
000100754 700__ $$aJourdain, G.
000100754 700__ $$aDecker, L.
000100754 700__ $$aEne, L.
000100754 700__ $$aHainaut, M.
000100754 700__ $$aVan der Kelen, E.
000100754 700__ $$aDelforge, M.
000100754 700__ $$ade Martino, M.
000100754 700__ $$aTovo, PA.
000100754 700__ $$aPatrizia, O.
000100754 700__ $$aLarovere, D.
000100754 700__ $$aRuggeri, M.
000100754 700__ $$aFaldella, G.
000100754 700__ $$aBaldi, F.
000100754 700__ $$aBadolato, R.
000100754 700__ $$aMontagnani, C.
000100754 700__ $$aVenturini, E.
000100754 700__ $$aLisi, C.
000100754 700__ $$aDi Biagio, A.
000100754 700__ $$aTaramasso, L.
000100754 700__ $$aGiacomet, V.
000100754 700__ $$aErba, P.
000100754 700__ $$aEsposito, S.
000100754 700__ $$aLipreri, R.
000100754 700__ $$aSalvini, F.
000100754 700__ $$aTagliabue, C.
000100754 700__ $$aCellini, M.
000100754 700__ $$aBruzzese, E.
000100754 700__ $$aLo Vecchio, A.
000100754 700__ $$aRampon, O.
000100754 700__ $$aDona, D.
000100754 700__ $$aRomano, A.
000100754 700__ $$aDodi, I.
000100754 700__ $$aMaccabruni, A.
000100754 700__ $$aConsolini, R.
000100754 700__ $$aBernardi, S.
000100754 700__ $$aKuekou, HT.
000100754 700__ $$aGenovese, O.
000100754 700__ $$aOlmeo, P.
000100754 700__ $$aCristiano, L.
000100754 700__ $$aMazza, A.
000100754 700__ $$aGabiano, C.
000100754 700__ $$aGarazzino, S.
000100754 700__ $$aPellegatta, A.
000100754 700__ $$aPajkrt, D.
000100754 700__ $$aScherpbier, HJ.
000100754 700__ $$aWeijsenfeld, AM.
000100754 700__ $$ade Boer, CG.
000100754 700__ $$aJurriaans, S.
000100754 700__ $$aBack, NKT.
000100754 700__ $$aZaaijer, HL.
000100754 700__ $$aBerkhout, B.
000100754 700__ $$aCornelissen, MTE.
000100754 700__ $$aSchinkel, CJ.
000100754 700__ $$aWolthers, KC.
000100754 700__ $$aFraaij, PLA.
000100754 700__ $$avan Rossum, AMC.
000100754 700__ $$aVermont, CL.
000100754 700__ $$avan der Knaap, LC.
000100754 700__ $$aVisser, EG.
000100754 700__ $$aBoucher, CAB.
000100754 700__ $$aKoopmans, MPG.
000100754 700__ $$avan Kampen, JJA.
000100754 700__ $$aPas, SD.
000100754 700__ $$aHenriet, SSV.
000100754 700__ $$avan de Flier, M.
000100754 700__ $$avan Aerde, K.
000100754 700__ $$aStrik-Albers, R.
000100754 700__ $$aRahamat-Langendoen, J.
000100754 700__ $$aStelma, FF.
000100754 700__ $$aScholvinck, EH.
000100754 700__ $$ade Groot-de Jonge, H.
000100754 700__ $$aNiesters, HGM.
000100754 700__ $$avan Leer-Buter, CC.
000100754 700__ $$aKnoester, M.
000100754 700__ $$aBont, LJ.
000100754 700__ $$aGeelen, SPM.
000100754 700__ $$aWolfs, TFW.
000100754 700__ $$aNauta, N.
000100754 700__ $$aSchuurman, R.
000100754 700__ $$aVerduyn-Lunel, F.
000100754 700__ $$aWensing, AMJ.
000100754 700__ $$aReiss, P.
000100754 700__ $$aZaheri, S.
000100754 700__ $$aBezemer, DO.
000100754 700__ $$avan Sighem, AI.
000100754 700__ $$aSmit, C.
000100754 700__ $$aWit, FWMN.
000100754 700__ $$aHillebregt, M.
000100754 700__ $$ade Jong, A.
000100754 700__ $$aWoudstra, T.
000100754 700__ $$aBergsma, D.
000100754 700__ $$aGrivell, S.
000100754 700__ $$aMeijering, R.
000100754 700__ $$aRaethke, M.
000100754 700__ $$aRutkens, T.
000100754 700__ $$ade Groot, L.
000100754 700__ $$avan den Akker, M.
000100754 700__ $$aBakker, Y.
000100754 700__ $$aBezemer, M.
000100754 700__ $$aEl Berkaoui, A.
000100754 700__ $$aGeerlinks, J.
000100754 700__ $$aKoops, J.
000100754 700__ $$aKruijne, E.
000100754 700__ $$aLodewijk, C.
000100754 700__ $$aLucas, E.
000100754 700__ $$avan der Meer, R.
000100754 700__ $$aMunjishvili, L.
000100754 700__ $$aPaling, E.
000100754 700__ $$aPeeck, B.
000100754 700__ $$aRee, C.
000100754 700__ $$aRegtop, R.
000100754 700__ $$aRuijs, Y.
000100754 700__ $$avan de Sande, L.
000100754 700__ $$aSchoorl, M.
000100754 700__ $$aSchnorr, P.
000100754 700__ $$aTuijn, E.
000100754 700__ $$aVeenenberg, L.
000100754 700__ $$avan der Vliet, S.
000100754 700__ $$aWisse, A.
000100754 700__ $$aWitte, EC.
000100754 700__ $$aTuk, B.
000100754 700__ $$aPopielska, J.
000100754 700__ $$aPokorska-Spiewak, M.
000100754 700__ $$aOldakowska, A.
000100754 700__ $$aZawadka, K.
000100754 700__ $$aCoupland, U.
000100754 700__ $$aDoroba, M.
000100754 700__ $$aVoronin, E.
000100754 700__ $$aMiloenko, M.
000100754 700__ $$aLabutina, S.
000100754 700__ $$aSoler-Palacin, P.
000100754 700__ $$aFrick, MA.
000100754 700__ $$aPerez-Hoyos, S.
000100754 700__ $$aMur, A.
000100754 700__ $$aLopez, N.
000100754 700__ $$aMendez, M.
000100754 700__ $$aMayol, L.
000100754 700__ $$aVallmanya, T.
000100754 700__ $$aCalavia, O.
000100754 700__ $$aGarcia, L.
000100754 700__ $$aColl, M.
000100754 700__ $$aPineda, V.
000100754 700__ $$aRius, N.
000100754 700__ $$aRovira, N.
000100754 700__ $$aDuenas, J.
000100754 700__ $$aGamell, A.
000100754 700__ $$aFortuny, C.
000100754 700__ $$aNoguera-Julian, A.
000100754 700__ $$aMellado, MJ.
000100754 700__ $$aEscosa, L.
000100754 700__ $$aHortelano, MG.
000100754 700__ $$aSainz, T.
000100754 700__ $$aGonzalez-Tome, MI.
000100754 700__ $$aRojo, P.
000100754 700__ $$aBlazquez, D.
000100754 700__ $$aPrieto, L.
000100754 700__ $$aGuillen, S.
000100754 700__ $$aSaavedra, J.
000100754 700__ $$aSantos, M.
000100754 700__ $$aMunoz, MA.
000100754 700__ $$aRuiz, B.
000100754 700__ $$aMc Phee, CF.
000100754 700__ $$ade Ory, SJ.
000100754 700__ $$aAlvarez, S.
000100754 700__ $$aRoa, MA.
000100754 700__ $$aBeceiro, J.
000100754 700__ $$aMartinez, J.
000100754 700__ $$aBadillo, K.
000100754 700__ $$aApilanez, M.
000100754 700__ $$aPocheville, I.
000100754 700__ $$aGarrote, E.
000100754 700__ $$aColino, E.
000100754 700__ $$aSirvent, JG.
000100754 700__ $$aGarzon, M.
000100754 700__ $$aRoman, V.
000100754 700__ $$aMontesdeoca, A.
000100754 700__ $$aMateo, M.
000100754 700__ $$aMunoz, MJ.
000100754 700__ $$aAngulo, R.
000100754 700__ $$aNeth, O.
000100754 700__ $$aFalcon, L.
000100754 700__ $$aTerol, P.
000100754 700__ $$aSantos, JL.
000100754 700__ $$aMoreno, D.
000100754 700__ $$aLendinez, F.
000100754 700__ $$aGrande, A.
000100754 700__ $$aRomero, FJ.
000100754 700__ $$aPerez, C.
000100754 700__ $$aLillo, M.
000100754 700__ $$aLosada, B.
000100754 700__ $$aHerranz, M.
000100754 700__ $$aBustillo, M.
000100754 700__ $$aGuerrero, C.
000100754 700__ $$0(orcid)0000-0001-8346-0544$$aCollado, P.$$uUniversidad de Zaragoza
000100754 700__ $$aCouceiro, JA.
000100754 700__ $$aPerez, A.
000100754 7102_ $$11010$$2670$$aUniversidad de Zaragoza$$bDpto. Pediatría Radiol.Med.Fís$$cÁrea Pediatría
000100754 773__ $$g33, 12 (2019), 1897-1910$$pAIDS$$tAIDS (London, England)$$x0269-9370
000100754 8564_ $$s459330$$uhttps://zaguan.unizar.es/record/100754/files/texto_completo.pdf$$yVersión publicada
000100754 8564_ $$s2305576$$uhttps://zaguan.unizar.es/record/100754/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000100754 909CO $$ooai:zaguan.unizar.es:100754$$particulos$$pdriver
000100754 951__ $$a2021-03-17-11:42:23
000100754 980__ $$aARTICLE