Resumen: The knowledge acquired during university education about organ donation and transplantation (ODT) decisively influences the information future health professionals transmit. This is important in ODT where the participation of the general public is essential to obtain organs. Objective: To determine notions of Spanish medicine and nursing students on ODT and its relationship with attitude toward ODT. Methods and Design: and design. We conducted a sociologic, multicenter, and observational study. The population for our study consisted of medical and nursing students in Spanish universities. Our database was the Collaborative International Donor Project, stratified by geographic area and academic course. A validated questionnaire (PCID-DTO-RIOS) was self-administered and completed anonymously. Our sample consisted of 9598 medical and 10, 566 nursing students (99% confidence interval; precision of ±1%), stratified by geographic area and year of study. Results: The completion rate for our study was 90%. Only 20% (n=3640) of students thought their notions on ODT were good; 41% (n=7531) thought their notions were normal; 36% (n=6550) thought their notions were scarce. Comparing groups, there were differences between those who believed that their notions on ODT were good (44% nursing vs 56% medical students; P < .000), and those who believed it scarce (54% nursing vs 46% medical students; P < .000). Notions on ODT were related with attitude toward the donation of one''s own organs: those who considered their notions were good were more in favor then those who considered it scarce (88% vs 72%; P < .000). Conclusion: Only 20% of Spanish medical and nursing students thought their notions on ODT were good. Having good knowledge is related to a favorable attitude towards ODT. Receiving specific information on the subject could improve their knowledge about ODT during their training. Idioma: Inglés DOI: 10.1016/j.transproceed.2020.01.086 Año: 2020 Publicado en: Transplantation Proceedings 52, 5 (2020), 1428-1431 ISSN: 0041-1345 Factor impacto JCR: 1.066 (2020) Categ. JCR: IMMUNOLOGY rank: 160 / 162 = 0.988 (2020) - Q4 - T3 Categ. JCR: TRANSPLANTATION rank: 24 / 25 = 0.96 (2020) - Q4 - T3 Categ. JCR: SURGERY rank: 187 / 212 = 0.882 (2020) - Q4 - T3 Factor impacto SCIMAGO: 0.373 - Transplantation (Q3) - Surgery (Q3)