000101171 001__ 101171
000101171 005__ 20210902121633.0
000101171 0247_ $$2doi$$a10.1002/ijgo.13140
000101171 0248_ $$2sideral$$a117992
000101171 037__ $$aART-2020-117992
000101171 041__ $$aeng
000101171 100__ $$aEspiau Romera, A.
000101171 245__ $$aHE4 tumor marker as a predictive factor for lymphatic metastasis in endometrial cancer
000101171 260__ $$c2020
000101171 5060_ $$aAccess copy available to the general public$$fUnrestricted
000101171 5203_ $$aEndometrial cancer is the most common genital cancer in high-resource countries. Treatment is essentially surgical, but the role of lymphadenectomy in the treatment of low-stage and low-grade tumors has not been defined. Although no tumor factors have been validated for use as preoperative prognostic markers of endometrial cancer at yet, human epididymis protein 4 (HE4) has received much interest as a potential diagnostic and prognostic tumor marker. Since 2008, several studies have explored its utility in the management of endometrial cancer: HE4 may be a useful preoperative prognostic marker because it is associated with lymphatic metastasis and other unfavorable factors in endometrial cancer. In addition, some studies have explored a HE4 cutoff value to classify patients according to lymph node involvement. HE4 might be beneficial as a serum marker that helps clinicians in the decision-making algorithm for treatment of endometrial cancer, enabling them to perform individualized operations and decrease the adverse effects of unnecessary surgery.
000101171 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000101171 590__ $$a3.561$$b2020
000101171 591__ $$aOBSTETRICS & GYNECOLOGY$$b20 / 83 = 0.241$$c2020$$dQ1$$eT1
000101171 592__ $$a0.895$$b2020
000101171 593__ $$aObstetrics and Gynecology$$c2020$$dQ2
000101171 593__ $$aMedicine (miscellaneous)$$c2020$$dQ2
000101171 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/acceptedVersion
000101171 700__ $$aCuesta Guardiola, T.
000101171 700__ $$aBenito Vielba, M.
000101171 700__ $$0(orcid)0000-0002-8218-1460$$aDe Bonrostro Torralba, C.$$uUniversidad de Zaragoza
000101171 700__ $$aCoronado Martín, P.J.
000101171 700__ $$aBaquedano Mainar, L.
000101171 7102_ $$11013$$2645$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Obstetricia y Ginecología
000101171 773__ $$g149, 3 (2020), 265-268$$pInt. j. gynaecol. obstet.$$tInternational Journal of Gynecology and Obstetrics$$x0020-7292
000101171 8564_ $$s39235$$uhttps://zaguan.unizar.es/record/101171/files/texto_completo.pdf$$yPostprint
000101171 8564_ $$s1281659$$uhttps://zaguan.unizar.es/record/101171/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000101171 909CO $$ooai:zaguan.unizar.es:101171$$particulos$$pdriver
000101171 951__ $$a2021-09-02-08:54:35
000101171 980__ $$aARTICLE