000101259 001__ 101259
000101259 005__ 20230519145406.0
000101259 0247_ $$2doi$$a10.1016/j.lfs.2021.119200
000101259 0248_ $$2sideral$$a122758
000101259 037__ $$aART-2021-122758
000101259 041__ $$aeng
000101259 100__ $$0(orcid)0000-0001-9585-0187$$aSaviron-Cornudella, Ricardo$$uUniversidad de Zaragoza
000101259 245__ $$aScreening of severe acute respiratory syndrome coronavirus-2 infection during labor and delivery using polymerase chain reaction and immunoglobulin testing
000101259 260__ $$c2021
000101259 5060_ $$aAccess copy available to the general public$$fUnrestricted
000101259 5203_ $$aAims
To assess severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection during labor and delivery with polymerase chain reaction (PCR) and using immunoglobulin G and M testing to correlate with maternal and perinatal outcomes.
Main methods
Pregnant women admitted for labor and delivery at two Spanish hospitals were screened for SARS-CoV-2 infection by PCR test and by detection of serum immunoglobulins G and M. Maternal and perinatal outcomes were compared in women with laboratory evidence of SARS-CoV-2 infection with those with negative tests.
Key findings
Between March 31st and September 30th, 2020, 1211 pregnant women were screened for SARS-CoV-2 infection. The prevalence of laboratory evidence of SARS-CoV-2 infections was 5.4% (n = 65), corresponding to (i) 22 ongoing infections at admission, including two with mild clinical symptoms and 20 asymptomatic women; (ii) 43 cases of previous SARS-CoV-2 exposure; (iii) and 1146 women who were negative for both SARS-CoV-2 PCR and serological test. None of the screened mothers required hospital admission for coronavirus disease before or after delivery, nor were any of the newborns admitted to the intensive care unit. All newborns from mothers with positive PCR on admission were PCR negative. There were no significant differences in maternal or perinatal outcomes among the three studied groups.
Significance
Ongoing or previous SARS-CoV-2 infection with asymptomatic or mild clinical symptoms detected during screening in pregnant women at labor and delivery do not have a higher rate of adverse maternal or perinatal outcomes.
000101259 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000101259 590__ $$a6.78$$b2021
000101259 592__ $$a1.132$$b2021
000101259 594__ $$a8.0$$b2021
000101259 591__ $$aPHARMACOLOGY & PHARMACY$$b36 / 279 = 0.129$$c2021$$dQ1$$eT1
000101259 593__ $$aMedicine (miscellaneous)$$c2021$$dQ1
000101259 591__ $$aMEDICINE, RESEARCH & EXPERIMENTAL$$b33 / 140 = 0.236$$c2021$$dQ1$$eT1
000101259 593__ $$aBiochemistry, Genetics and Molecular Biology (miscellaneous)$$c2021$$dQ1
000101259 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000101259 700__ $$aVillalba, Ana
000101259 700__ $$0(orcid)0000-0002-3007-302X$$aEsteban, Luis M
000101259 700__ $$0(orcid)0000-0003-4720-8231$$aTajada, Mauricio$$uUniversidad de Zaragoza
000101259 700__ $$aRodríguez-Solanilla, Belén
000101259 700__ $$aAndeyro-Garcia, Mercedes
000101259 700__ $$aZapardiel, Javier
000101259 700__ $$aRite, Segundo
000101259 700__ $$aCastan-Larraz, Berta
000101259 700__ $$0(orcid)0000-0002-2801-416X$$aPérez-López, Faustino
000101259 7102_ $$11003$$2027$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Anatom.Embriol.Humana
000101259 7102_ $$11013$$2645$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Obstetricia y Ginecología
000101259 773__ $$g271, 119200 (2021), j.lfs.2021.119200 [7 pp.]$$pLife sci.$$tLIFE SCIENCES$$x0024-3205
000101259 8564_ $$s681830$$uhttps://zaguan.unizar.es/record/101259/files/texto_completo.pdf$$yVersión publicada
000101259 8564_ $$s1016131$$uhttps://zaguan.unizar.es/record/101259/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000101259 909CO $$ooai:zaguan.unizar.es:101259$$particulos$$pdriver
000101259 951__ $$a2023-05-18-13:47:44
000101259 980__ $$aARTICLE