101259 20230519145406.0 doi 10.1016/j.lfs.2021.119200 sideral 122758 ART-2021-122758 eng Saviron-Cornudella, Ricardo Universidad de Zaragoza (orcid)0000-0001-9585-0187 Screening of severe acute respiratory syndrome coronavirus-2 infection during labor and delivery using polymerase chain reaction and immunoglobulin testing 2021 Access copy available to the general public Unrestricted Aims To assess severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection during labor and delivery with polymerase chain reaction (PCR) and using immunoglobulin G and M testing to correlate with maternal and perinatal outcomes. Main methods Pregnant women admitted for labor and delivery at two Spanish hospitals were screened for SARS-CoV-2 infection by PCR test and by detection of serum immunoglobulins G and M. Maternal and perinatal outcomes were compared in women with laboratory evidence of SARS-CoV-2 infection with those with negative tests. Key findings Between March 31st and September 30th, 2020, 1211 pregnant women were screened for SARS-CoV-2 infection. The prevalence of laboratory evidence of SARS-CoV-2 infections was 5.4% (n = 65), corresponding to (i) 22 ongoing infections at admission, including two with mild clinical symptoms and 20 asymptomatic women; (ii) 43 cases of previous SARS-CoV-2 exposure; (iii) and 1146 women who were negative for both SARS-CoV-2 PCR and serological test. None of the screened mothers required hospital admission for coronavirus disease before or after delivery, nor were any of the newborns admitted to the intensive care unit. All newborns from mothers with positive PCR on admission were PCR negative. There were no significant differences in maternal or perinatal outcomes among the three studied groups. Significance Ongoing or previous SARS-CoV-2 infection with asymptomatic or mild clinical symptoms detected during screening in pregnant women at labor and delivery do not have a higher rate of adverse maternal or perinatal outcomes. info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 6.78 2021 PHARMACOLOGY & PHARMACY 36 / 279 = 0.129 2021 Q1 T1 MEDICINE, RESEARCH & EXPERIMENTAL 33 / 140 = 0.236 2021 Q1 T1 1.132 2021 Medicine (miscellaneous) 2021 Q1 Biochemistry, Genetics and Molecular Biology (miscellaneous) 2021 Q1 8.0 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Villalba, Ana Esteban, Luis M (orcid)0000-0002-3007-302X Tajada, Mauricio Universidad de Zaragoza (orcid)0000-0003-4720-8231 Rodríguez-Solanilla, Belén Andeyro-Garcia, Mercedes Zapardiel, Javier Rite, Segundo Castan-Larraz, Berta Pérez-López, Faustino (orcid)0000-0002-2801-416X 1003 027 Universidad de Zaragoza Dpto. Anatom.Histolog.Humanas Area Anatom.Embriol.Humana 1013 645 Universidad de Zaragoza Dpto. Cirugía Área Obstetricia y Ginecología 271, 119200 (2021), j.lfs.2021.119200 [7 pp.] Life sci. LIFE SCIENCES 0024-3205 681830 http://zaguan.unizar.es/record/101259/files/texto_completo.pdf Versión publicada 1016131 http://zaguan.unizar.es/record/101259/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:101259 articulos driver 2023-05-18-13:47:44 ARTICLE