000101265 001__ 101265 000101265 005__ 20230622083319.0 000101265 0248_ $$2sideral$$a123833 000101265 037__ $$aART-2020-123833 000101265 041__ $$aeng 000101265 100__ $$0(orcid)0000-0001-9585-0187$$aSavirón-Cornudella, Ricardo$$uUniversidad de Zaragoza 000101265 245__ $$aCoronavirus disease 2019 (COVID-19) and human pregnancy: a scoping review 000101265 260__ $$c2020 000101265 5060_ $$aAccess copy available to the general public$$fUnrestricted 000101265 5203_ $$aThe coronavirus disease 2019 (COVID-19) is caused by the infection with a coronavirus (SARS-CoV-2). Pregnants present mild or moderate symptoms, with 5% presenting as a severe pneumonia. Prevalence and evolution of COVID-19 in pregnancy is similar to that of the general population, including the risk of maternal death. Radiography, computed tomography or ultrasound imaging are pivotal for the diagnosis and given the clinical suspicion of COVID-19 pneumonia. Lab findings include lymphocytopenia, thrombocytopenia, leukopenia, and the elevation of D-dimer and ferritin. To date, there is no specific treatment or vaccination for COVID-19; yet clinical management in pregnants is also similar to that of the general population, with prophylactic antibiotic treatment for bacterial pneumonia and oxygen support. Thromboprophylaxis should be indicated in severe cases, given that pregnancy is a hypercoagulable state that may be exacerbated by COVID-19. Hospital management should focus on treating the mother and protecting the newborn and the health personnel. Regarding COVID-19 and perinatal outcomes, premature deliveries are mainly associated to iatrogenic pregnancy termination through cesarean section aimed conserving maternal well-being. To date, vertical transmission to the fetus has not been demonstrated, neither intrauterine, nor through the birth canal. The virus has not been detected in vaginal fluids, or in breast milk. Breastfeeding may be allowed depending on maternal and neonatal health status. There are still many unknown issues, although there is a continuous update of scientific information related to pregnancy and COVID-19. 000101265 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000101265 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000101265 700__ $$aAltamirano-Barcia, Iván E. 000101265 700__ $$aChedraui, Peter 000101265 700__ $$aAndeyro-García, Mercedes 000101265 700__ $$0(orcid)0000-0003-4720-8231$$aTajada, Mauricio$$uUniversidad de Zaragoza 000101265 700__ $$0(orcid)0000-0002-2801-416X$$aPérez-López, Faustino R. 000101265 7102_ $$11003$$2027$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Anatom.Embriol.Humana 000101265 7102_ $$11013$$2645$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Obstetricia y Ginecología 000101265 773__ $$g1, 2 (2020), 70-75$$pGynecol. reprod. endocrinol. metab.$$tGynecological and Reproductive Endocrinology and Metabolism$$x2710-2297 000101265 85641 $$uhttps://gremjournal.com/wp-content/uploads/2020/06/01_Perez-Lopez.pdf$$zTexto completo de la revista 000101265 8564_ $$s244478$$uhttps://zaguan.unizar.es/record/101265/files/texto_completo.pdf$$yVersión publicada 000101265 8564_ $$s3159162$$uhttps://zaguan.unizar.es/record/101265/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000101265 909CO $$ooai:zaguan.unizar.es:101265$$particulos$$pdriver 000101265 951__ $$a2023-06-21-15:02:50 000101265 980__ $$aARTICLE