101640 20230519145441.0 doi 10.3390/nu13030723 sideral 124114 ART-2021-124114 eng Malo, Sara Universidad de Zaragoza (orcid)0000-0002-7194-8275 Identifying clusters of adherence to cardiovascular risk reduction behaviors and persistence with medication in new lipid-lowering drug users. Impact on healthcare utilization 2021 Access copy available to the general public Unrestricted We sought to identify specific profiles of new lipid-lowering drug users based on adherence to a healthy lifestyle and persistence with medication, and to characterize co-morbidities, co-treatments, and healthcare utilization for each of the profiles identified. Observational study in 517 participants in the Aragon Workers’ Health Study (AWHS) without previous cardiovascular disease (CVD) and who initiated lipid-lowering therapy. Data were collected from workplace medical examinations and administrative health databases (2010– 2018). Using cluster analysis, we identified distinct patient profiles based on persistence with therapy and lifestyle. We then compared characteristics, morbidity, and healthcare utilization across clusters. Participants were aggregated into four clusters based on persistence with therapy, smoking status, adherence to Mediterranean diet, and physical activity. In cluster 1 (n = 113), comprising those with a healthiest lifestyle (14.2% smokers, 84.0% with medium-high adherence to Mediterranean diet, high physical activity), 16.8% were persistent. In cluster 3 (n = 108), comprising patients with the least healthy lifestyle (100% smokers, poor adherence to the Mediterranean diet, low level of physical activity), all were non-persistent. Clusters 2 (n = 150) and 4 (n = 146) both comprised patients with intermediate lifestyle be-haviors, but differed in terms of persistence (100 and 0%, respectively). Compared with other clusters, the burden of morbidity, cardiovascular score, and healthcare utilization were lower in cluster 1. The healthy adherer effect was only observed in new lipid-lowering drug users of certain profiles. Furthermore, we found that differences in adherence to lifestyle and medication recommendations for CVD prevention influenced morbidity burden and healthcare utilization. info:eu-repo/grantAgreement/ES/ISCIII-FEDER-FIS/PI17-01704 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 6.706 2021 NUTRITION & DIETETICS 15 / 90 = 0.167 2021 Q1 T1 1.287 2021 Nutrition and Dietetics 2021 Q1 Food Science 2021 Q1 7.9 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Rabanaque, María José Universidad de Zaragoza (orcid)0000-0002-6671-5661 Maldonado, Lina Universidad de Zaragoza (orcid)0000-0003-1647-3462 Moreno-Franco, Belén Universidad de Zaragoza (orcid)0000-0003-0604-5042 Chaure-Pardos, Armando Lallana, María Jesús (orcid)0000-0001-7587-9716 Rodrigo, María Pilar Aguilar-Palacio, Isabel Universidad de Zaragoza (orcid)0000-0001-7293-701X 4014 623 Universidad de Zaragoza Dpto. Economía Aplicada Área Métodos Cuant.Econ.Empres 1011 615 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Medic.Prevent.Salud Públ. 13, 3 (2021), 723 [14 pp.] Nutrients Nutrients 2072-6643 691209 http://zaguan.unizar.es/record/101640/files/texto_completo.pdf Versión publicada 2745501 http://zaguan.unizar.es/record/101640/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:101640 articulos driver 2023-05-18-14:32:21 ARTICLE