000102066 001__ 102066
000102066 005__ 20210618112019.0
000102066 0247_ $$2doi$$a10.1016/j.tvjl.2019.105392
000102066 0248_ $$2sideral$$a114805
000102066 037__ $$aART-2019-114805
000102066 041__ $$aeng
000102066 100__ $$aFernández-Parra, R.
000102066 245__ $$aUse of computational fluid dynamics to compare upper airway pressures and airflow resistance in brachycephalic, mesocephalic, and dolichocephalic dogs
000102066 260__ $$c2019
000102066 5060_ $$aAccess copy available to the general public$$fUnrestricted
000102066 5203_ $$aBrachycephalic dog breeds are prone to breathing difficulties because of their upper airway anatomy. Several surgical techniques exist to correct anatomical pathologies and common surgical approaches aim to correct functional abnormalities in the nares and/or the soft palate. However, further research is needed to improve clinical outcomes. This study evaluated air pressure and airflow resistance in the upper airways and trachea in nine sedated, sternally recumbent dogs of different skull types (dolichocephalic, n = 3; mesocephalic, n = 3; brachycephalic, n = 3). CT images were acquired from the nostrils to the caudal border of the lungs and geometrical reconstruction of the upper airway and trachea was performed. Analysis of computational fluid dynamics was performed using inspiratory flow adapted to bodyweight for each dog. Flow (L/min) and pressure (cmH2O) were computed for the entire upper airway and trachea. Resistance (cmH2O/L/min) was calculated using pressure differences between the nose, larynx, and trachea. In this pilot study, statistical comparisons were not performed. Pressure maps, airflow, and resistance were similar in dolichocephalic and mesocephalic breeds. Median pressure difference (3.76 cmH2O) and resistance (0.154 cmH2O/L/min) between the nose and larynx were numerically higher in brachycephalic dogs than in other breeds (0.45 cmH2O and 0.016 cmH2O/L/min, respectively). Median pressure difference (0.205 cmH2O) and resistance (0.009 cmH2O/L/min) between the larynx and trachea was numerically similar in all dogs, except for the English bulldog. The methodology used in this preliminary study to quantify airflow characteristics such as pressure and resistance could improve the understanding of brachycephalic obstruction airway syndrome.
000102066 536__ $$9info:eu-repo/grantAgreement/ES/AEI-MINECO-FEDER/DP12017-83259-R$$9info:eu-repo/grantAgreement/ES/ISCIII/CIBER-BBN
000102066 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000102066 590__ $$a2.115$$b2019
000102066 591__ $$aVETERINARY SCIENCES$$b25 / 142 = 0.176$$c2019$$dQ1$$eT1
000102066 592__ $$a0.893$$b2019
000102066 593__ $$aVeterinary (miscellaneous)$$c2019$$dQ1
000102066 593__ $$aAnimal Science and Zoology$$c2019$$dQ1
000102066 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000102066 700__ $$aPey, P.
000102066 700__ $$aZilberstein, L.
000102066 700__ $$0(orcid)0000-0002-0116-2736$$aMalvè, M.
000102066 773__ $$g253 (2019), 105392 [10 pp.]$$pVet. j.$$tVeterinary Journal$$x1090-0233
000102066 8564_ $$s304618$$uhttps://zaguan.unizar.es/record/102066/files/texto_completo.pdf$$yPostprint
000102066 8564_ $$s1300321$$uhttps://zaguan.unizar.es/record/102066/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000102066 909CO $$ooai:zaguan.unizar.es:102066$$particulos$$pdriver
000102066 951__ $$a2021-06-18-11:14:45
000102066 980__ $$aARTICLE