102115 20230519145405.0 doi 10.1039/d0na00980f sideral 124338 ART-2021-124338 eng Song, L. Preparation of Cu cluster catalysts by simultaneous cooling-microwave heating: application in radical cascade annulation 2021 Access copy available to the general public Unrestricted One of the hallmarks of microwave irradiation is its selective heating mechanism. In the past 30 years, alternative designs of chemical reactors have been introduced, where the microwave (MW) absorber occupies a limited reactor volume but the surrounding environment is MW transparent. This advantage results in a different heating profile or even the possibility to quickly cool down the system. Simultaneous cooling-microwave heating has been largely adopted for organic chemical transformations. However, to the best of our knowledge there are no reports of its application in the field of nanocluster synthesis. In this work, we propose an innovative one-pot procedure for the synthesis of Cu nanoclusters. The cluster nucleation was selectively MW-activated inside the pores of a highly ordered mesoporous substrate. Once the nucleation event occurred, the crystallization reaction was instantaneously quenched, precluding the growth events and favoring the production of Cu clusters with a homogenous size distribution. Herein, we demonstrated that Cu nanoclusters could be successfully adopted for radical cascade annulations ofN-alkoxybenzamides, resulting in various tricyclic and tetracyclic isoquinolones, which are widely present in lots of natural products and bioactive compounds. Compared to reported homogeneous methods, supported Cu nanoclusters provide a better platform for a green, sustainable and efficient heterogeneous approach for the synthesis of tricyclic and tetracyclic isoquinolones, avoiding a variety of toxic waste/byproducts and metal contamination in the final products. info:eu-repo/grantAgreement/EC/H2020/721290/EU/European Training Network for Continuous Sonication and Microwave Reactors/COSMIC This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 721290-COSMIC info:eu-repo/semantics/openAccess by-nc http://creativecommons.org/licenses/by-nc/3.0/es/ 5.598 2021 CHEMISTRY, MULTIDISCIPLINARY 56 / 180 = 0.311 2021 Q2 T1 MATERIALS SCIENCE, MULTIDISCIPLINARY 111 / 345 = 0.322 2021 Q2 T1 NANOSCIENCE & NANOTECHNOLOGY 55 / 109 = 0.505 2021 Q3 T2 1.043 2021 Atomic and Molecular Physics, and Optics 2021 Q1 Materials Science (miscellaneous) 2021 Q1 Engineering (miscellaneous) 2021 Q1 Bioengineering 2021 Q1 5.7 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Manno, R. Universidad de Zaragoza (orcid)0000-0001-9391-3594 Ranjan, P. Sebastian, V. Universidad de Zaragoza (orcid)0000-0002-6873-5244 Irusta, S. Universidad de Zaragoza (orcid)0000-0002-2966-9088 Mallada, R. Universidad de Zaragoza (orcid)0000-0002-4758-9380 Van Meervelt, L. Santamaria, J. Universidad de Zaragoza (orcid)0000-0002-8701-9745 Van der Eycken, E.V. 5005 555 Universidad de Zaragoza Dpto. Ing.Quím.Tecnol.Med.Amb. Área Ingeniería Química 5005 790 Universidad de Zaragoza Dpto. Ing.Quím.Tecnol.Med.Amb. Área Tecnologi. Medio Ambiente 3, 3 (2021), 1087-1095 Nanoscale Advances 2516-0230 884870 http://zaguan.unizar.es/record/102115/files/texto_completo.pdf Versión publicada 2684008 http://zaguan.unizar.es/record/102115/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:102115 articulos driver 2023-05-18-13:46:34 ARTICLE