000102131 001__ 102131
000102131 005__ 20230519145407.0
000102131 0247_ $$2doi$$a10.3390/antiox10020320
000102131 0248_ $$2sideral$$a124362
000102131 037__ $$aART-2021-124362
000102131 041__ $$aeng
000102131 100__ $$aLlorente-Cantarero, Francisco Jesús
000102131 245__ $$aRelationship between physical activity, oxidative stress, and total plasma antioxidant capacity in spanish children from the genobox study
000102131 260__ $$c2021
000102131 5060_ $$aAccess copy available to the general public$$fUnrestricted
000102131 5203_ $$aThe World Health Organization has recommended performing at least 60 min a day of moderate-to-vigorous physical activity (MVPA) and reducing sedentarism in children and adolescents to offer significant health benefits and mitigate health risks. Physical fitness and sports practice seem to improve oxidative stress (OS) status during childhood. However, to our knowledge, there are no data regarding the influence of objectively-measured physical activity (PA) and sedentarism on OS status in children and adolescents. The present study aimed to evaluate the influence of moderate and vigorous PA and sedentarism on OS and plasma total antioxidant capacity (TAC) in a selected Spanish population of 216 children and adolescents from the GENOBOX study. PA (light, moderate, and vigorous) and sedentarism (i.e., sedentary time (ST)) were measured by accelerometry. A Physical Activity-Sedentarism Score (PASS) was developed integrating moderate and vigorous PA and ST levels. Urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) and isoprostane F2a (F2-IsoPs), as markers of OS, were determined by ELISA; and TAC was estimated by colorimetry using an antioxidant kit. A higher PASS was associated with lower plasma TAC and urinary 8OHdG and F2-IsoPs, showing a better redox profile. Reduced OS markers (8-OHdG and F2-IsoPs) in children with higher PASS may diminish the need of maintaining high concentrations of antioxidants in plasma during rest to achieve redox homeostasis.
000102131 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI11-01425$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI11-02042$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI11-02059$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI16-00871$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI16-01205$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI16-01301$$9info:eu-repo/grantAgreement/ES/ISCIII/i-PFIS-IFI17-00048$$9info:eu-repo/grantAgreement/ES/MSCBS-ISCIII-FEDER/RETICS-RD12-0026-0015
000102131 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000102131 590__ $$a7.675$$b2021
000102131 592__ $$a1.008$$b2021
000102131 594__ $$a6.5$$b2021
000102131 591__ $$aBIOCHEMISTRY & MOLECULAR BIOLOGY$$b50 / 297 = 0.168$$c2021$$dQ1$$eT1
000102131 593__ $$aBiochemistry$$c2021$$dQ1
000102131 591__ $$aFOOD SCIENCE & TECHNOLOGY$$b12 / 144 = 0.083$$c2021$$dQ1$$eT1
000102131 593__ $$aPhysiology$$c2021$$dQ1
000102131 591__ $$aCHEMISTRY, MEDICINAL$$b4 / 63 = 0.063$$c2021$$dQ1$$eT1
000102131 593__ $$aMolecular Biology$$c2021$$dQ1
000102131 593__ $$aClinical Biochemistry$$c2021$$dQ1
000102131 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000102131 700__ $$aAguilar-Gómez, Francisco Javier
000102131 700__ $$aLeis, Rosaura
000102131 700__ $$aBueno, Gloria
000102131 700__ $$0(orcid)0000-0002-3850-8235$$aRupérez, Azahara I.
000102131 700__ $$aAnguita-Ruiz, Augusto
000102131 700__ $$aVázquez-Cobela, Rocío
000102131 700__ $$aMesa, María Dolores
000102131 700__ $$aMoreno, Luis A.
000102131 700__ $$aGil, Ángel
000102131 700__ $$aAguilera, Concepción María
000102131 700__ $$aGil-Campos, Mercedes
000102131 773__ $$g10, 2 (2021), 320 [14 pp.]$$pAntioxidants$$tAntioxidants$$x2076-3921
000102131 8564_ $$s1310052$$uhttps://zaguan.unizar.es/record/102131/files/texto_completo.pdf$$yVersión publicada
000102131 8564_ $$s2842502$$uhttps://zaguan.unizar.es/record/102131/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000102131 909CO $$ooai:zaguan.unizar.es:102131$$particulos$$pdriver
000102131 951__ $$a2023-05-18-13:50:04
000102131 980__ $$aARTICLE