000102178 001__ 102178
000102178 005__ 20230519145442.0
000102178 0247_ $$2doi$$a10.3390/ani11030691
000102178 0248_ $$2sideral$$a124133
000102178 037__ $$aART-2021-124133
000102178 041__ $$aeng
000102178 100__ $$0(orcid)0000-0001-5105-6133$$aAcín, Cristina$$uUniversidad de Zaragoza
000102178 245__ $$aClassical and atypical scrapie in sheep and goats: Review on the etiology, genetic factors, pathogenesis, diagnosis, and control measures of both diseases
000102178 260__ $$c2021
000102178 5060_ $$aAccess copy available to the general public$$fUnrestricted
000102178 5203_ $$aPrion diseases, such as scrapie, are neurodegenerative diseases with a fatal outcome, caused by a conformational change of the cellular prion protein (PrPC), originating with the pathogenic form (PrPSc). Classical scrapie in small ruminants is the paradigm of prion diseases, as it was the first transmissible spongiform encephalopathy (TSE) described and is the most studied. It is necessary to understand the etiological properties, the relevance of the transmission pathways, the infectivity of the tissues, and how we can improve the detection of the prion protein to encourage detection of the disease. The aim of this review is to perform an overview of classical and atypical scrapie disease in sheep and goats, detailing those special issues of the disease, such as genetic fac-tors, diagnostic procedures, and surveillance approaches carried out in the European Union with the objective of controlling the dissemination of scrapie disease.
000102178 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000102178 590__ $$a3.231$$b2021
000102178 592__ $$a0.61$$b2021
000102178 594__ $$a2.7$$b2021
000102178 591__ $$aVETERINARY SCIENCES$$b16 / 145 = 0.11$$c2021$$dQ1$$eT1
000102178 593__ $$aVeterinary (miscellaneous)$$c2021$$dQ1
000102178 591__ $$aAGRICULTURE, DAIRY & ANIMAL SCIENCE$$b13 / 63 = 0.206$$c2021$$dQ1$$eT1
000102178 593__ $$aAnimal Science and Zoology$$c2021$$dQ1
000102178 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/publishedVersion
000102178 700__ $$0(orcid)0000-0002-2746-3932$$aBolea, Rosa$$uUniversidad de Zaragoza
000102178 700__ $$0(orcid)0000-0002-2787-9671$$aMonzón, Marta$$uUniversidad de Zaragoza
000102178 700__ $$0(orcid)0000-0002-7453-1766$$aMonleón, Eva$$uUniversidad de Zaragoza
000102178 700__ $$0(orcid)0000-0001-6629-6842$$aMoreno, Bernardino$$uUniversidad de Zaragoza
000102178 700__ $$0(orcid)0000-0003-3352-740X$$aFilali, Hicham
000102178 700__ $$0(orcid)0000-0002-1590-3347$$aMarín, Belén$$uUniversidad de Zaragoza
000102178 700__ $$aSola, Diego$$uUniversidad de Zaragoza
000102178 700__ $$0(orcid)0000-0002-0388-9429$$aBetancor, Marina$$uUniversidad de Zaragoza
000102178 700__ $$0(orcid)0000-0001-9773-7460$$aGuijarro, Isabel M.
000102178 700__ $$0(orcid)0000-0002-8752-5146$$aGarcía, Mirta$$uUniversidad de Zaragoza
000102178 700__ $$0(orcid)0000-0002-6158-691X$$aVargas, Antonio
000102178 700__ $$0(orcid)0000-0002-7173-7216$$aBadiola, Juan José$$uUniversidad de Zaragoza
000102178 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal
000102178 7102_ $$11003$$2443$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Histología
000102178 773__ $$g11, 3 (2021), 691 [20 pp.]$$pAnimals (Basel)$$tAnimals$$x2076-2615
000102178 8564_ $$s1188484$$uhttps://zaguan.unizar.es/record/102178/files/texto_completo.pdf$$yVersión publicada
000102178 8564_ $$s2775528$$uhttps://zaguan.unizar.es/record/102178/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000102178 909CO $$ooai:zaguan.unizar.es:102178$$particulos$$pdriver
000102178 951__ $$a2023-05-18-14:34:10
000102178 980__ $$aARTICLE