000102210 001__ 102210
000102210 005__ 20220908120515.0
000102210 0247_ $$2doi$$a10.22037/ghfbb.v14i1.1788
000102210 0248_ $$2sideral$$a124378
000102210 037__ $$aART-2021-124378
000102210 041__ $$aeng
000102210 100__ $$aPeña-Galo, E.
000102210 245__ $$aSocioeconomic and demographic factors associated with failure in Helicobacter pylori eradication using the standard triple therapy
000102210 260__ $$c2021
000102210 5060_ $$aAccess copy available to the general public$$fUnrestricted
000102210 5203_ $$aAim: To evaluate the influence of socioeconomic and demographic factors on the eradication rate of H. pylori, using standard triple therapy Background: the efficacy of the standard triple therapy (STT) for H. pylori eradication has decreased with the rise of antibiotic resistance. Other factors could influence the eradication failure, although available results are conflicting. Methods: Retrospective study, including adults with H. pylori infection treated de novo with STT (proton pump inhibitor, amoxicillin and clarithromycin). Eradication success was assessed by 13C-urea breath test. Demographic and socioeconomics variables were evaluated and correlated with eradication treatment outcome. The confounder variables were controlled by logistic regression analysis. Results: Out of 902 patients with H. pylori diagnosis, 693 met inclusion criteria (average age 53 years; females 55.2%). Nonsignificant differences were observed in relation to economics income between rural and urban areas (p=0.316). The eradication rate of H. pylori was 71.1%: male 78.9% vs female 65.9%, urban area 73.4% vs rural area 64.1%. With reference to age, income and nationality, the eradication rates were similar in all groups. According to logistic regression analysis, females had almost twice more likelihood of eradication failure in relation to males (OR 1.92; 95%CI: 1.38-2.72); and rural residents had OR 1.55 (95%CI: 1.03- 2.33) for having eradication failure in contrast with urban population. Conclusion: Female gender and rural residence are factors associated with H. Pylori eradication failure with standard triple therapy.
000102210 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000102210 592__ $$a0.354$$b2021
000102210 594__ $$a2.7$$b2021
000102210 593__ $$aHepatology$$c2021$$dQ3
000102210 593__ $$aGastroenterology$$c2021$$dQ3
000102210 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000102210 700__ $$aGotor, J.
000102210 700__ $$aHarb, Y.
000102210 700__ $$0(orcid)0000-0001-6522-6682$$aAlonso, M.$$uUniversidad de Zaragoza
000102210 700__ $$aAlcedo, J.
000102210 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000102210 773__ $$g14, 1 (2021), 53-58$$tGastroenterology and Hepatology from Bed to Bench$$x2008-2258
000102210 8564_ $$s237903$$uhttps://zaguan.unizar.es/record/102210/files/texto_completo.pdf$$yVersión publicada
000102210 8564_ $$s2377441$$uhttps://zaguan.unizar.es/record/102210/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000102210 909CO $$ooai:zaguan.unizar.es:102210$$particulos$$pdriver
000102210 951__ $$a2022-09-08-11:54:50
000102210 980__ $$aARTICLE