000106220 001__ 106220
000106220 005__ 20230519145439.0
000106220 0247_ $$2doi$$a10.1038/s41598-021-87410-9
000106220 0248_ $$2sideral$$a124444
000106220 037__ $$aART-2021-124444
000106220 041__ $$aeng
000106220 100__ $$aRoy, J.F.
000106220 245__ $$aThe TELE-DD project on treatment nonadherence in the population with type 2 diabetes and comorbid depression
000106220 260__ $$c2021
000106220 5060_ $$aAccess copy available to the general public$$fUnrestricted
000106220 5203_ $$aDiabetic patients have increased depression rates, diminished quality of life, and higher death rates due to depression comorbidity or diabetes complications. Treatment adherence (TA) and the maintenance of an adequate and competent self-care are crucial factors to reach optimal glycaemic control and stable quality of life in these patients. In this report, we present the baseline population analyses in phase I of the TELE-DD project, a three-phased population-based study in 23 Health Centres from the Aragonian Health Service Sector II in Zaragoza, Spain. The objectives of the present report are: (1) to determine the point prevalence of T2D and clinical depression comorbidity and treatment nonadherence; (2) to test if HbA1c and LDL-C, as primary DM outcomes, are related to TA in this population; and (3) to test if these DM primary outcomes are associated with TA independently of shared risk factors for DM and depression, and patients’ health behaviours. A population of 7,271 patients with type-2 diabetes and comorbid clinical depression was investigated for inclusion. Individuals with confirmed diagnoses and drug treatment for both illnesses (n = 3340) were included in the current phase I. A point prevalence of 1.9% was found for the T2D-depression comorbidity. The prevalence of patients nonadherent to treatment for these diseases was 35.4%. Multivariate analyses confirmed that lower diabetes duration, increased yearly PCS visits, HbA1c and LDL-C levels were independently related to treatment nonadherence. These findings informed the development of a telephonic monitoring platform for treatment of nonadherence for people with diabetes and comorbid depression and further trial, cost-effectiveness, and prognostic studies (phases II and III).
000106220 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII-MECD-IISZ/FI17-00180$$9info:eu-repo/grantAgreement/ES/ISCIII-MINECO-FEDER/PI19-00805$$9info:eu-repo/grantAgreement/ES/ISCIII/RD16-0007-0005
000106220 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000106220 590__ $$a4.997$$b2021
000106220 592__ $$a1.005$$b2021
000106220 591__ $$aMULTIDISCIPLINARY SCIENCES$$b19 / 74 = 0.257$$c2021$$dQ2$$eT1
000106220 593__ $$aMultidisciplinary$$c2021$$dQ1
000106220 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000106220 700__ $$0(orcid)0000-0003-2448-1630$$aLozano del Hoyo, M.L.$$uUniversidad de Zaragoza
000106220 700__ $$aUrcola Pardo, F.
000106220 700__ $$aMonreal-Bartolomé, A.
000106220 700__ $$aGracia Ruiz, D.C.
000106220 700__ $$aGómez Borao, M.M.
000106220 700__ $$aArtigas Alcázar, A.B.
000106220 700__ $$aMartínez Casbas, J.P.
000106220 700__ $$aAceituno Casas, A.
000106220 700__ $$aAndaluz Funcia, M.T.
000106220 700__ $$0(orcid)0000-0002-3797-4218$$aGarcía Campayo, J.$$uUniversidad de Zaragoza
000106220 700__ $$0(orcid)0000-0002-6455-119X$$aFernández Rodrigo, M.T.$$uUniversidad de Zaragoza
000106220 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000106220 7102_ $$11007$$2745$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Psiquiatría
000106220 773__ $$g11 (2021), 8889 [10 pp.]$$pSci. rep. (Nat. Publ. Group)$$tScientific reports (Nature Publishing Group)$$x2045-2322
000106220 8564_ $$s920900$$uhttps://zaguan.unizar.es/record/106220/files/texto_completo.pdf$$yVersión publicada
000106220 8564_ $$s2569000$$uhttps://zaguan.unizar.es/record/106220/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000106220 909CO $$ooai:zaguan.unizar.es:106220$$particulos$$pdriver
000106220 951__ $$a2023-05-18-14:29:18
000106220 980__ $$aARTICLE