106220 20250122145317.0 doi 10.1038/s41598-021-87410-9 sideral 124444 ART-2021-124444 eng Roy, J.F. The TELE-DD project on treatment nonadherence in the population with type 2 diabetes and comorbid depression 2021 Access copy available to the general public Unrestricted Diabetic patients have increased depression rates, diminished quality of life, and higher death rates due to depression comorbidity or diabetes complications. Treatment adherence (TA) and the maintenance of an adequate and competent self-care are crucial factors to reach optimal glycaemic control and stable quality of life in these patients. In this report, we present the baseline population analyses in phase I of the TELE-DD project, a three-phased population-based study in 23 Health Centres from the Aragonian Health Service Sector II in Zaragoza, Spain. The objectives of the present report are: (1) to determine the point prevalence of T2D and clinical depression comorbidity and treatment nonadherence; (2) to test if HbA1c and LDL-C, as primary DM outcomes, are related to TA in this population; and (3) to test if these DM primary outcomes are associated with TA independently of shared risk factors for DM and depression, and patients’ health behaviours. A population of 7,271 patients with type-2 diabetes and comorbid clinical depression was investigated for inclusion. Individuals with confirmed diagnoses and drug treatment for both illnesses (n = 3340) were included in the current phase I. A point prevalence of 1.9% was found for the T2D-depression comorbidity. The prevalence of patients nonadherent to treatment for these diseases was 35.4%. Multivariate analyses confirmed that lower diabetes duration, increased yearly PCS visits, HbA1c and LDL-C levels were independently related to treatment nonadherence. These findings informed the development of a telephonic monitoring platform for treatment of nonadherence for people with diabetes and comorbid depression and further trial, cost-effectiveness, and prognostic studies (phases II and III). info:eu-repo/grantAgreement/ES/ISCIII-MECD-IISZ/FI17-00180 info:eu-repo/grantAgreement/ES/ISCIII-MINECO-FEDER/PI19-00805 info:eu-repo/grantAgreement/ES/ISCIII/RD16-0007-0005 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 4.997 2021 MULTIDISCIPLINARY SCIENCES 19 / 74 = 0.257 2021 Q2 T1 1.005 2021 Multidisciplinary 2021 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Lozano del Hoyo, M.L. Universidad de Zaragoza (orcid)0000-0003-2448-1630 Urcola Pardo, F. Universidad de Zaragoza (orcid)0000-0001-7049-8295 Monreal-Bartolomé, A. (orcid)0000-0003-2088-2007 Gracia Ruiz, D.C. Gómez Borao, M.M. Artigas Alcázar, A.B. Martínez Casbas, J.P. Aceituno Casas, A. Andaluz Funcia, M.T. García Campayo, J. Universidad de Zaragoza (orcid)0000-0002-3797-4218 Fernández Rodrigo, M.T. Universidad de Zaragoza (orcid)0000-0002-6455-119X 1006 255 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Enfermería 1007 745 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Psiquiatría 11 (2021), 8889 [10 pp.] Sci. rep. (Nat. Publ. Group) Scientific reports (Nature Publishing Group) 2045-2322 920900 http://zaguan.unizar.es/record/106220/files/texto_completo.pdf Versión publicada 2569000 http://zaguan.unizar.es/record/106220/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:106220 articulos driver 2025-01-22-14:52:03 ARTICLE