106252 20230622083316.0 doi 10.1016/j.coemr.2020.06.006 sideral 119880 ART-2020-119880 eng Aguilar-Gomez, F.J. Metabolic syndrome before puberty: Myth or reality? 2020 Access copy available to the general public Unrestricted Metabolic syndrome (MetS) is defined as a cluster of alterations related with insulin resistance (obesity, dyslipidemia, hypertension, and impaired glucose metabolism), which are associated with a higher risk of cardiovascular disease in adults. Several definitions have been proposed for older children and adolescents. However, no definitions have been made in accordance with pubertal status, and those in prepubertal state have not received attention enough, despite there are data suggesting the early presence of risk factors. The new insights concerning healthy and unhealthy metabolic status or the addition of novel metabolic risk biomarkers, may contribute to the knowledge about the development of MetS in children. This manuscript reviews the available evidence on MetS during childhood, focusing on the prepubertal period. info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI051968 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI11-02042 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI16-00871 info:eu-repo/grantAgreement/ES/ISCIII/RETICS-RD12-0026-0015 info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 0.264 2020 Endocrinology, Diabetes and Metabolism 2020 Q3 info:eu-repo/semantics/review info:eu-repo/semantics/acceptedVersion Bueno-Lozano, G. Universidad de Zaragoza (orcid)0000-0002-0902-387X Leis, R. Aguilera, C.M. Gil-Campos, M. 1011 670 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Pediatría 14 (2020), 97-103 Current Opinion in Endocrine and Metabolic Research 2451-9650 108673 http://zaguan.unizar.es/record/106252/files/texto_completo.pdf Postprint 942216 http://zaguan.unizar.es/record/106252/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:106252 articulos driver 2023-06-21-15:02:12 ARTICLE