000106623 001__ 106623
000106623 005__ 20210902121832.0
000106623 0247_ $$2doi$$a10.1016/j.theriogenology.2020.07.030
000106623 0248_ $$2sideral$$a119863
000106623 037__ $$aART-2020-119863
000106623 041__ $$aeng
000106623 100__ $$0(orcid)0000-0003-2827-3054$$aAbecia, J.A.$$uUniversidad de Zaragoza
000106623 245__ $$aPolymorphisms of the melatonin receptor 1A (MTNR1A) gene influence the age at first mating in autumn-born ram-lambs and sexual activity of adult rams in spring
000106623 260__ $$c2020
000106623 5060_ $$aAccess copy available to the general public$$fUnrestricted
000106623 5203_ $$aThe aim of this study was to determine whether polymorphisms of the melatonin receptor 1A (MTNR1A) gene influence the age at first mating in autumn-born ram-lambs and influence the out-of-season sexual activity of adult rams. In experiment 1, 24 Rasa Aragonesa ram-lambs born in September were genotyped for their RsaI and MnlI allelic variants of the MTNR1A gene, and the date of their first mounting with ejaculation after a period of semen collection training was documented. In experiment 2, the reproductive behavior, testicle size, and plasma testosterone concentrations of 18 adult rams (6 rams for each RsaI genotype) were recorded at the beginning (March) and end (May) of the seasonal anestrus. The number of days of training to achieve the first mating with ejaculation in T/T (C/C: 85.17 ± 12.08 C/T: 86.60 ± 18.87; T/T; 26.50 ± 24.50 d; P < 0.05), and G/G ram-lambs (G/G: 51.57 ± 14.99; A/G: 95.58 ± 10.95 d; P < 0.05) was significantly fewer than it was in the other genotypes. Likewise, for the RsaI genotype, 55% of the vulva-sniffing (P < 0.001), 48% of the approaches (P < 0.01), 48% of the mountings (P < 0.05) and 49% total activities (P < 0.001) were performed by T/T rams in March, and 50% of the sexual events in May (P < 0.001). For the Mnll variant, G/G rams performed a significantly (P < 0.001) larger proportion of the vulva-sniffing (41%), approaches (46%) and total activities (40%) in March, and 52% of the vulva-sniffing (P < 0.001), 43%, of the approaches (P < 0.001), 46% of the mountings (P < 0.05), and 47% of the total activities (P < 0.001) in May. Scrotal circumference, testicular volume, and plasma testosterone concentrations did not differ significantly among genotypes. Results confirmed that the polymorphisms of the MTNR1A gene sequence can influence reproductive performance in young and adult rams. Autumn-born ram-lambs that carried the T/T or G/G genotype had an advanced ability to reproduce, and T/T or G/G adult rams exhibited the most intense reproductive behavior. Genotyping might be a useful procedure for identifying the correct and rational use of rams in modern sheep farming.
000106623 536__ $$9info:eu-repo/grantAgreement/ES/MCYT/AGL2017-82118-R
000106623 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000106623 590__ $$a2.74$$b2020
000106623 591__ $$aVETERINARY SCIENCES$$b21 / 146 = 0.144$$c2020$$dQ1$$eT1
000106623 591__ $$aREPRODUCTIVE BIOLOGY$$b20 / 30 = 0.667$$c2020$$dQ3$$eT3
000106623 592__ $$a0.815$$b2020
000106623 593__ $$aAnimal Science and Zoology$$c2020$$dQ1
000106623 593__ $$aSmall Animals$$c2020$$dQ1
000106623 593__ $$aFood Animals$$c2020$$dQ1
000106623 593__ $$aEquine$$c2020$$dQ1
000106623 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000106623 700__ $$aMura, M.C.
000106623 700__ $$0(orcid)0000-0003-3929-5064$$aCarvajal-Serna, M.$$uUniversidad de Zaragoza
000106623 700__ $$aPulinas, L.
000106623 700__ $$aMacías, A.
000106623 700__ $$0(orcid)0000-0003-1997-4262$$aCasao, A.$$uUniversidad de Zaragoza
000106623 700__ $$0(orcid)0000-0002-2312-6402$$aPérez-Pe, R.$$uUniversidad de Zaragoza
000106623 700__ $$aCarcangiu, V.
000106623 7102_ $$11002$$2819$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Zoología
000106623 7102_ $$12008$$2700$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Producción Animal
000106623 773__ $$g157 (2020), 42-47$$p1879-3231]$$tTHERIOGENOLOGY$$x0093-691X
000106623 8564_ $$s235528$$uhttps://zaguan.unizar.es/record/106623/files/texto_completo.pdf$$yPostprint
000106623 8564_ $$s759149$$uhttps://zaguan.unizar.es/record/106623/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000106623 909CO $$ooai:zaguan.unizar.es:106623$$particulos$$pdriver
000106623 951__ $$a2021-09-02-10:17:24
000106623 980__ $$aARTICLE