000106664 001__ 106664
000106664 005__ 20230519145425.0
000106664 0247_ $$2doi$$a10.3390/plants10071363
000106664 0248_ $$2sideral$$a124496
000106664 037__ $$aART-2021-124496
000106664 041__ $$aeng
000106664 100__ $$aLanga-Lomba, N.
000106664 245__ $$aAntifungal ativity against Botryosphaeriaceae fungi of the hydro-methanolic extract of Silybum marianum capitula conjugated with stevioside
000106664 260__ $$c2021
000106664 5060_ $$aAccess copy available to the general public$$fUnrestricted
000106664 5203_ $$aSilybum marianum (L.) Gaertn, viz. milk thistle, has been the focus of research efforts in the past few years, albeit almost exclusively restricted to the medicinal properties of its fruits (achenes). Given that other milk thistle plant organs and tissues have been scarcely investigated for the presence of bioactive compounds, in this study, we present a phytochemical analysis of the extracts of S. marianum capitula during the flowering phenological stage (stage 67). Gas chromatography–mass spectroscopy results evidenced the presence of high contents of coniferyl alcohol (47.4%), and secondarily of ferulic acid ester, opening a new valorization strategy of this plant based on the former high-added-value component. Moreover, the application of the hydro-methanolic extracts as an antifungal agent has been also explored. Specifically, their activity against three fungal species responsible for the so-called Botryosphaeria dieback of grapevine (Neofusicoccum parvum, Dothiorella viticola and Diplodia seriata) has been assayed both in vitro and in vivo. From the mycelial growth inhibition assays, the best results (EC90 values of 303, 366, and 355 μg·mL−1 for N. parvum, D. viticola, and D. seriata, respectively) were not obtained for the hydroalcoholic extract alone, but after its conjugation with stevioside, which resulted in a strong synergistic behavior. Greenhouse experiments confirmed the efficacy of the conjugated complexes, pointing to the potential of the combination of milk thistle extracts with stevioside as a promising plant protection product in organic Viticulture.
000106664 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000106664 590__ $$a4.658$$b2021
000106664 592__ $$a0.765$$b2021
000106664 594__ $$a3.6$$b2021
000106664 591__ $$aPLANT SCIENCES$$b39 / 240 = 0.162$$c2021$$dQ1$$eT1
000106664 593__ $$aPlant Science$$c2021$$dQ1
000106664 593__ $$aEcology, Evolution, Behavior and Systematics$$c2021$$dQ1
000106664 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000106664 700__ $$aBuzón-Durán, L.
000106664 700__ $$aSánchez-Hernández, E.
000106664 700__ $$0(orcid)0000-0003-2713-2786$$aMartín Ramos, P.$$uUniversidad de Zaragoza
000106664 700__ $$0(orcid)0000-0003-3009-0935$$aCasanova Gascón, J.$$uUniversidad de Zaragoza
000106664 700__ $$aMartín Gil, J.
000106664 700__ $$aGonzález-García, V.
000106664 7102_ $$15011$$2500$$aUniversidad de Zaragoza$$bDpto. CC.Agrar.y Medio Natural$$cArea Ingeniería Agroforestal
000106664 7102_ $$15011$$2705$$aUniversidad de Zaragoza$$bDpto. CC.Agrar.y Medio Natural$$cÁrea Producción Vegetal
000106664 773__ $$g10, 7 (2021), 1363 [15 pp.]$$tPlants$$x2223-7747
000106664 8564_ $$s1024322$$uhttps://zaguan.unizar.es/record/106664/files/texto_completo.pdf$$yVersión publicada
000106664 8564_ $$s2765718$$uhttps://zaguan.unizar.es/record/106664/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000106664 909CO $$ooai:zaguan.unizar.es:106664$$particulos$$pdriver
000106664 951__ $$a2023-05-18-14:11:46
000106664 980__ $$aARTICLE