106669 20250912141054.0 doi 10.3390/app11125665 sideral 124666 ART-2021-124666 eng Hernández Secorún, Mar Universidad de Zaragoza (orcid)0000-0001-9678-3449 Exercise and manual therapy for diabetic peripheral neuropathy: a systematic review 2021 Access copy available to the general public Unrestricted Background: Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes mellitus (DM). Control of hyperglycaemia as well as surgical decompression are effective treatments for these patients. However, surgery is not indicated for all candidates. Manual therapy and physical exercise have been shown to be effective for peripheral neuropathies, and exercise for DM. The aim is to review the effectiveness of manual therapy and/or exercise in patients with DPN. (2) Methods: Randomised controlled clinical trials comparing the effects of manual therapy and/or exercise on pain, function and/or balance were selected. The search strategy was performed in PubMed, PEDro, Scopus, Cochrane and Web of Science databases. The PRISMA statement was followed. (3) Results: A total of 656 articles were registered, and 29 were selected. There was little consensus on DPN criteria selection. Aerobic, strength and balance exercises are beneficial for DPN. Sessions of 30–60 min, three times per week for 8 weeks seems to be the most used dose. Manual therapy is effective in the short term. A combination of both modalities was more beneficial than alone in one study. (4) Conclusions: Exercise and manual therapy are beneficial for patients with DPN. More studies should be carried out for analysing the potential effect of combining manual therapy and exercise. info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 2.838 2021 PHYSICS, APPLIED 76 / 161 = 0.472 2021 Q2 T2 ENGINEERING, MULTIDISCIPLINARY 39 / 92 = 0.424 2021 Q2 T2 CHEMISTRY, MULTIDISCIPLINARY 100 / 179 = 0.559 2021 Q3 T2 MATERIALS SCIENCE, MULTIDISCIPLINARY 218 / 344 = 0.634 2021 Q3 T2 0.507 2021 Computer Science Applications 2021 Q2 Engineering (miscellaneous) 2021 Q2 Process Chemistry and Technology 2021 Q2 Materials Science (miscellaneous) 2021 Q2 Fluid Flow and Transfer Processes 2021 Q2 3.7 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Vidal Peracho, Concepción Universidad de Zaragoza (orcid)0000-0003-1444-7949 Márquez Gonzalvo, Sergio Corral de Toro, Jaime Universidad de Zaragoza Müller Thyssen Uriarte, Julián Universidad de Zaragoza (orcid)0000-0002-9105-827X Rodríguez Sanz, Jacobo Lucha López, Orosia Universidad de Zaragoza (orcid)0000-0002-9930-3903 Tricás Moreno, José Miguel Universidad de Zaragoza (orcid)0000-0002-3583-5206 Hidalgo García, César Universidad de Zaragoza (orcid)0000-0001-7667-2178 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 1006 413 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Fisioterapia 11, 12 (2021), [31 pp.] Appl. sci. Applied Sciences (Switzerland) 2076-3417 1138144 http://zaguan.unizar.es/record/106669/files/texto_completo.pdf Versión publicada 2773592 http://zaguan.unizar.es/record/106669/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:106669 articulos driver 2025-09-12-14:09:34 ARTICLE