doi:10.3390/foods10030649engNoriega-Fernández, E.Sone, I.Astráin-Redín, L.Prabhu, L.Sivertsvik, M.Álvarez, I.Cebrián, G.Innovative ultrasound-assisted approaches towards reduction of heavy metals and Iodine in macroalgal biomassART-2021-124766The aim of this work was to evaluate the potential of ultrasound (US), alone or in combination with mild heating and/or EDTA towards reduction of As, Cd, I, and Hg content of Laminaria hyperborea. Concentrations of As, Cd, I, and Hg of 56.29, 0.596, 7340, and <0.01 mg kg−1 of dry weight, respectively, were found in L. hyperborea blades. Treatment with US at 50 °C increased approx. 2-fold the amount of As released, although did not affect significantly the content of Cd or I, as compared to control (no US) samples. Reducing the temperature to 8 °C significantly decreased the effect of US, but heating at 80 °C did not cause a significant effect as compared to treatments at 50 °C. On the other hand, treatment with 0.1 N EDTA at 50 °C enhanced the percentage of Cd released by approximately 7-fold, regardless of sonication. In the present work, the combination of US and EDTA at 50 °C for 5 min led to a significant reduction of the As (32%), Cd (52%) and I (31%) content in L. hyperborea, thus improving the product’s safety for consumers.2021http://zaguan.unizar.es/record/10734110.3390/foods10030649http://zaguan.unizar.es/record/107341oai:zaguan.unizar.es:107341Foods 10, 3 (2021), 649 [13 pp.]byhttp://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccess