000107342 001__ 107342
000107342 005__ 20230519145440.0
000107342 0247_ $$2doi$$a10.3390/ijms22126266
000107342 0248_ $$2sideral$$a124732
000107342 037__ $$aART-2021-124732
000107342 041__ $$aeng
000107342 100__ $$aPastor-Navarro, B.
000107342 245__ $$aActive surveillance in prostate cancer: role of available biomarkers in daily practice
000107342 260__ $$c2021
000107342 5060_ $$aAccess copy available to the general public$$fUnrestricted
000107342 5203_ $$aProstate cancer (PCa) is the most commonly diagnosed cancer in men. The diagnosis is currently based on PSA levels, which are associated with overdiagnosis and overtreatment. Moreover, most PCas are localized tumours; hence, many patients with low-/very low-risk PCa could benefit from active surveillance (AS) programs instead of more aggressive, active treatments. Heterogeneity within inclusion criteria and follow-up strategies are the main controversial issues that AS presently faces. Many biomarkers are currently under investigation in this setting; however, none has yet demonstrated enough diagnostic ability as an independent predictor of pathological or clinical progression. This work aims to review the currently available literature on tissue, blood and urine biomarkers validated in clinical practice for the management of AS patients.
000107342 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000107342 590__ $$a6.208$$b2021
000107342 592__ $$a1.176$$b2021
000107342 594__ $$a6.9$$b2021
000107342 591__ $$aBIOCHEMISTRY & MOLECULAR BIOLOGY$$b69 / 297 = 0.232$$c2021$$dQ1$$eT1
000107342 593__ $$aComputer Science Applications$$c2021$$dQ1
000107342 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b50 / 180 = 0.278$$c2021$$dQ2$$eT1
000107342 593__ $$aInorganic Chemistry$$c2021$$dQ1
000107342 593__ $$aSpectroscopy$$c2021$$dQ1
000107342 593__ $$aOrganic Chemistry$$c2021$$dQ1
000107342 593__ $$aPhysical and Theoretical Chemistry$$c2021$$dQ1
000107342 593__ $$aMolecular Biology$$c2021$$dQ1
000107342 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/publishedVersion
000107342 700__ $$aRubio-Briones, J.
000107342 700__ $$0(orcid)0000-0003-0178-4567$$aBorque Fernando, Á.$$uUniversidad de Zaragoza
000107342 700__ $$0(orcid)0000-0002-3007-302X$$aEsteban Escaño, L. M.
000107342 700__ $$aDomínguez-Escrig, J. L.
000107342 700__ $$aLópez-Guerrero, J. A.
000107342 7102_ $$11013$$2817$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Urología
000107342 773__ $$g22, 12 (2021), 6266 [14 pp.]$$pInt. j. mol. sci.$$tInternational Journal of Molecular Sciences$$x1661-6596
000107342 8564_ $$s1031698$$uhttps://zaguan.unizar.es/record/107342/files/texto_completo.pdf$$yVersión publicada
000107342 8564_ $$s2710743$$uhttps://zaguan.unizar.es/record/107342/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000107342 909CO $$ooai:zaguan.unizar.es:107342$$particulos$$pdriver
000107342 951__ $$a2023-05-18-14:30:04
000107342 980__ $$aARTICLE